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Discovery of 5,7-Dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-ones as Highly Selective CDK2 Inhibitors.
Sokolsky A, Winterton S, Kennedy K, Drake K, Stump K, Huo L, Lo Y, Ye M, Covington M, Diamond S, Yang YO, Kim S, Yeleswaram S, Wu L, Yao W. Sokolsky A, et al. Among authors: kim s. ACS Med Chem Lett. 2022 Oct 6;13(11):1797-1804. doi: 10.1021/acsmedchemlett.2c00408. eCollection 2022 Nov 10. ACS Med Chem Lett. 2022. PMID: 36385925 Free PMC article.
Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2.
Hummel JR, Xiao KJ, Yang JC, Epling LB, Mukai K, Ye Q, Xu M, Qian D, Huo L, Weber M, Roman V, Lo Y, Drake K, Stump K, Covington M, Kapilashrami K, Zhang G, Ye M, Diamond S, Yeleswaram S, Macarron R, Deller MC, Wee S, Kim S, Wang X, Wu L, Yao W. Hummel JR, et al. Among authors: kim s. J Med Chem. 2024 Feb 22;67(4):3112-3126. doi: 10.1021/acs.jmedchem.3c02287. Epub 2024 Feb 7. J Med Chem. 2024. PMID: 38325398
Discovery of INCB159020, an Orally Bioavailable KRAS G12D Inhibitor.
Ye Q, Shvartsbart A, Li Z, Gan P, Policarpo RL, Qi C, Roach JJ, Zhu W, McCammant MS, Hu B, Li G, Yin H, Carlsen P, Hoang G, Zhao L, Susick R, Zhang F, Lai CT, Allali Hassani A, Epling LB, Gallion A, Kurzeja-Lipinski K, Gallagher K, Roman V, Farren MR, Kong W, Deller MC, Zhang G, Covington M, Diamond S, Kim S, Yao W, Sokolsky A, Wang X. Ye Q, et al. Among authors: kim s. J Med Chem. 2025 Jan 23;68(2):1924-1939. doi: 10.1021/acs.jmedchem.4c02662. Epub 2025 Jan 8. J Med Chem. 2025. PMID: 39772605
Global metabolomic alterations associated with endocrine-disrupting chemicals among pregnant individuals and newborns.
Puvvula J, Song LC, Zalewska KJ, Alexander A, Manz KE, Braun JM, Pennell KD, DeFranco EA, Ho SM, Leung YK, Huang S, Vuong AM, Kim SS, Percy Z, Bhashyam P, Lee R, Jones DP, Tran V, Kim DV, Calafat AM, Botelho JC, Chen A. Puvvula J, et al. Among authors: kim ss. Metabolomics. 2025 Jan 25;21(1):20. doi: 10.1007/s11306-024-02219-7. Metabolomics. 2025. PMID: 39863779
Prognostic performance of the two-step clinical care pathway in metabolic dysfunction-associated steatotic liver disease.
Cheuk-Fung Yip T, Lee HW, Lin H, Tsochatzis E, Petta S, Bugianesi E, Yoneda M, Zheng MH, Hagström H, Boursier J, Calleja JL, Boon-Bee Goh G, Chan WK, Gallego-Durán R, Sanyal AJ, de Lédinghen V, Newsome PN, Fan JG, Castéra L, Lai M, Fournier-Poizat C, Lai-Hung Wong G, Pennisi G, Armandi A, Nakajima A, Liu WY, Shang Y, de Saint-Loup M, Llop E, Jun Teh KK, Lara-Romero C, Asgharpour A, Mahgoub S, Sau-Wai Chan M, Canivet CM, Romero-Gomez M, Kim SU, Wai-Sun Wong V. Cheuk-Fung Yip T, et al. Among authors: kim su. J Hepatol. 2025 Jan 23:S0168-8278(25)00021-2. doi: 10.1016/j.jhep.2025.01.014. Online ahead of print. J Hepatol. 2025. PMID: 39863175
Label-free quantitative imaging of conjunctival goblet cells.
Park N, Jeon S, Kim S, Lee J, Ryu JS, Choi WJ, Yoon CH, Joo C, Kim KH. Park N, et al. Among authors: kim s. Ocul Surf. 2025 Jan 23:S1542-0124(25)00017-5. doi: 10.1016/j.jtos.2025.01.009. Online ahead of print. Ocul Surf. 2025. PMID: 39862966
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