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New C3H KitN824K/WT cancer mouse model develops late-onset malignant mammary tumors with high penetrance.
Klein-Rodewald T, Micklich K, Sanz-Moreno A, Tost M, Calzada-Wack J, Adler T, Klaften M, Sabrautzki S, Aigner B, Kraiger M, Gailus-Durner V, Fuchs H; German Mouse Clinic Consortium; Gründer A, Pahl H, Wolf E, Hrabe de Angelis M, Rathkolb B. Klein-Rodewald T, et al. Among authors: grunder a. Sci Rep. 2022 Nov 17;12(1):19793. doi: 10.1038/s41598-022-23218-5. Sci Rep. 2022. PMID: 36396684 Free PMC article.
MPN patients harbor recurrent truncating mutations in transcription factor NF-E2.
Jutzi JS, Bogeska R, Nikoloski G, Schmid CA, Seeger TS, Stegelmann F, Schwemmers S, Gründer A, Peeken JC, Gothwal M, Wehrle J, Aumann K, Hamdi K, Dierks C, Kamar Wang W, Döhner K, Jansen JH, Pahl HL. Jutzi JS, et al. Among authors: grunder a. J Exp Med. 2013 May 6;210(5):1003-19. doi: 10.1084/jem.20120521. J Exp Med. 2013. PMID: 23589569 Free PMC article.
Gab2 is Essential for Transformation by FLT3-ITD in Acute Myeloid Leukemia.
Sies K, Spohr C, Gründer A, Todorova R, Uhl FM, Huber J, Zeiser R, Pahl HL, Becker H, Aumann K, Brummer T, Halbach S. Sies K, et al. Among authors: grunder a. Hemasphere. 2019 Feb 22;3(2):e184. doi: 10.1097/HS9.0000000000000184. eCollection 2019 Apr. Hemasphere. 2019. PMID: 31723823 Free PMC article. No abstract available.
A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2.
Kaufmann KB, Gründer A, Hadlich T, Wehrle J, Gothwal M, Bogeska R, Seeger TS, Kayser S, Pham KB, Jutzi JS, Ganzenmüller L, Steinemann D, Schlegelberger B, Wagner JM, Jung M, Will B, Steidl U, Aumann K, Werner M, Günther T, Schüle R, Rambaldi A, Pahl HL. Kaufmann KB, et al. Among authors: grunder a. J Exp Med. 2012 Jan 16;209(1):35-50. doi: 10.1084/jem.20110540. Epub 2012 Jan 9. J Exp Med. 2012. PMID: 22231305 Free PMC article.
Epigenetic regulation of NFE2 overexpression in myeloproliferative neoplasms.
Peeken JC, Jutzi JS, Wehrle J, Koellerer C, Staehle HF, Becker H, Schoenwandt E, Seeger TS, Schanne DH, Gothwal M, Ott CJ, Gründer A, Pahl HL. Peeken JC, et al. Among authors: grunder a. Blood. 2018 May 3;131(18):2065-2073. doi: 10.1182/blood-2017-10-810622. Epub 2018 Mar 8. Blood. 2018. PMID: 29519804 Free PMC article.
69 results