Maurer TS - Search Results

1

Relationship of binding-site occupancy, transthyretin stabilisation and disease modification in patients with tafamidis-treated transthyretin amyloid cardiomyopathy.

Tess DA, Maurer TS, Li Z, Bulawa C, Fleming J, Moody AT. Tess DA, et al. Among authors: maurer ts. Amyloid. 2023 Jun;30(2):208-219. doi: 10.1080/13506129.2022.2145876. Epub 2022 Nov 18. Amyloid. 2023. PMID: 36399070 Free article.

2

Relationship between exposure and nonspecific binding of thirty-three central nervous system drugs in mice.

Maurer TS, Debartolo DB, Tess DA, Scott DO. Maurer TS, et al. Drug Metab Dispos. 2005 Jan;33(1):175-81. doi: 10.1124/dmd.104.001222. Epub 2004 Oct 22. Drug Metab Dispos. 2005. PMID: 15502010

3

A Study on Pharmacokinetics of Bosentan with Systems Modeling, Part 1: Translating Systemic Plasma Concentration to Liver Exposure in Healthy Subjects.

Li R, Niosi M, Johnson N, Tess DA, Kimoto E, Lin J, Yang X, Riccardi KA, Ryu S, El-Kattan AF, Maurer TS, Tremaine LM, Di L. Li R, et al. Among authors: maurer ts. Drug Metab Dispos. 2018 Apr;46(4):346-356. doi: 10.1124/dmd.117.078790. Epub 2018 Jan 12. Drug Metab Dispos. 2018. PMID: 29330218

4

A Physiologically Based in Silico Tool to Assess the Risk of Drug-Related Crystalluria.

Li Z, Litchfield J, Tess DA, Carlo AA, Eng H, Keefer C, Maurer TS. Li Z, et al. Among authors: maurer ts. J Med Chem. 2020 Jun 25;63(12):6489-6498. doi: 10.1021/acs.jmedchem.9b01995. Epub 2020 Mar 13. J Med Chem. 2020. PMID: 32130005

5

Influence of microsomal concentration on apparent intrinsic clearance: implications for scaling in vitro data.

Kalvass JC, Tess DA, Giragossian C, Linhares MC, Maurer TS. Kalvass JC, et al. Among authors: maurer ts. Drug Metab Dispos. 2001 Oct;29(10):1332-6. Drug Metab Dispos. 2001. PMID: 11560877

6

Theoretical Considerations for Direct Translation of Unbound Liver-to-Plasma Partition Coefficient from In Vitro to In Vivo.

Li Z, Di L, Maurer TS. Li Z, et al. Among authors: maurer ts. AAPS J. 2019 Mar 18;21(3):43. doi: 10.1208/s12248-019-0314-1. AAPS J. 2019. PMID: 30887138

7

Model-Based Assessment of Plasma Citrate Flux Into the Liver: Implications for NaCT as a Therapeutic Target.

Li Z, Erion DM, Maurer TS. Li Z, et al. Among authors: maurer ts. CPT Pharmacometrics Syst Pharmacol. 2016 Mar;5(3):132-9. doi: 10.1002/psp4.12062. Epub 2016 Mar 4. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27069776 Free PMC article.

8

Modeling Exposure to Understand and Predict Kidney Injury.

Li Z, Fisher C, Gardner I, Ghosh A, Litchfield J, Maurer TS. Li Z, et al. Among authors: maurer ts. Semin Nephrol. 2019 Mar;39(2):176-189. doi: 10.1016/j.semnephrol.2018.12.006. Semin Nephrol. 2019. PMID: 30827340 Review.

9

Discovery of potent and orally bioavailable heterocycle-based beta3-adrenergic receptor agonists, potential therapeutics for the treatment of obesity.

Lafontaine JA, Day RF, Dibrino J, Hadcock JR, Hargrove DM, Linhares M, Martin KA, Maurer TS, Nardone NA, Tess DA, Dasilva-Jardine P. Lafontaine JA, et al. Among authors: maurer ts. Bioorg Med Chem Lett. 2007 Sep 15;17(18):5245-50. doi: 10.1016/j.bmcl.2007.06.072. Epub 2007 Jun 30. Bioorg Med Chem Lett. 2007. PMID: 17632003

10

Potent and selective, sulfamide-based human beta 3-adrenergic receptor agonists.

Dow RL, Paight ES, Schneider SR, Hadcock JR, Hargrove DM, Martin KA, Maurer TS, Nardone NA, Tess DA, DaSilva-Jardine P. Dow RL, et al. Among authors: maurer ts. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3235-40. doi: 10.1016/j.bmcl.2004.03.089. Bioorg Med Chem Lett. 2004. PMID: 15149682

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