Hamers N - Search Results

1

PPARγ lipodystrophy mutants reveal intermolecular interactions required for enhancer activation.

Madsen MS, Broekema MF, Madsen MR, Koppen A, Borgman A, Gräwe C, Thomsen EGK, Westland D, Kranendonk MEG, Koerkamp MG, Hamers N, Bonvin AMJJ, Pittol JMR, Natarajan KN, Kersten S, Holstege FCP, Monajemi H, van Mil SWC, Vermeulen M, Kragelund BB, Cassiman D, Mandrup S, Kalkhoven E. Madsen MS, et al. Among authors: hamers n. Nat Commun. 2022 Nov 19;13(1):7090. doi: 10.1038/s41467-022-34766-9. Nat Commun. 2022. PMID: 36402763 Free PMC article.

2

Impaired peroxisome proliferator-activated receptor gamma function through mutation of a conserved salt bridge (R425C) in familial partial lipodystrophy.

Jeninga EH, van Beekum O, van Dijk AD, Hamers N, Hendriks-Stegeman BI, Bonvin AM, Berger R, Kalkhoven E. Jeninga EH, et al. Among authors: hamers n. Mol Endocrinol. 2007 May;21(5):1049-65. doi: 10.1210/me.2006-0485. Epub 2007 Feb 20. Mol Endocrinol. 2007. PMID: 17312272

3

Peroxisome proliferator-activated receptor gamma regulates expression of the anti-lipolytic G-protein-coupled receptor 81 (GPR81/Gpr81).

Jeninga EH, Bugge A, Nielsen R, Kersten S, Hamers N, Dani C, Wabitsch M, Berger R, Stunnenberg HG, Mandrup S, Kalkhoven E. Jeninga EH, et al. Among authors: hamers n. J Biol Chem. 2009 Sep 25;284(39):26385-93. doi: 10.1074/jbc.M109.040741. Epub 2009 Jul 24. J Biol Chem. 2009. PMID: 19633298 Free PMC article.

4

Characterisation of non-obese diabetic patients with marked insulin resistance identifies a novel familial partial lipodystrophy-associated PPARγ mutation (Y151C).

Visser ME, Kropman E, Kranendonk ME, Koppen A, Hamers N, Stroes ES, Kalkhoven E, Monajemi H. Visser ME, et al. Among authors: hamers n. Diabetologia. 2011 Jul;54(7):1639-44. doi: 10.1007/s00125-011-2142-4. Epub 2011 Apr 9. Diabetologia. 2011. PMID: 21479595 Free PMC article.

5

Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60.

Gao Y, Koppen A, Rakhshandehroo M, Tasdelen I, van de Graaf SF, van Loosdregt J, van Beekum O, Hamers N, van Leenen D, Berkers CR, Berger R, Holstege FC, Coffer PJ, Brenkman AB, Ovaa H, Kalkhoven E. Gao Y, et al. Among authors: hamers n. Nat Commun. 2013;4:2656. doi: 10.1038/ncomms3656. Nat Commun. 2013. PMID: 24141283 Free article.

6

The serine/threonine phosphatase PPM1B (PP2Cβ) selectively modulates PPARγ activity.

Tasdelen I, van Beekum O, Gorbenko O, Fleskens V, van den Broek NJ, Koppen A, Hamers N, Berger R, Coffer PJ, Brenkman AB, Kalkhoven E. Tasdelen I, et al. Among authors: hamers n. Biochem J. 2013 Apr 1;451(1):45-53. doi: 10.1042/BJ20121113. Biochem J. 2013. PMID: 23320500

7

The adipogenic acetyltransferase Tip60 targets activation function 1 of peroxisome proliferator-activated receptor gamma.

van Beekum O, Brenkman AB, Grøntved L, Hamers N, van den Broek NJ, Berger R, Mandrup S, Kalkhoven E. van Beekum O, et al. Among authors: hamers n. Endocrinology. 2008 Apr;149(4):1840-9. doi: 10.1210/en.2007-0977. Epub 2007 Dec 20. Endocrinology. 2008. PMID: 18096664

8

Natural killer T cells in adipose tissue prevent insulin resistance.

Schipper HS, Rakhshandehroo M, van de Graaf SF, Venken K, Koppen A, Stienstra R, Prop S, Meerding J, Hamers N, Besra G, Boon L, Nieuwenhuis EE, Elewaut D, Prakken B, Kersten S, Boes M, Kalkhoven E. Schipper HS, et al. Among authors: hamers n. J Clin Invest. 2012 Sep;122(9):3343-54. doi: 10.1172/JCI62739. Epub 2012 Aug 6. J Clin Invest. 2012. PMID: 22863618 Free PMC article.

9

Muscle-specific inflammation induced by MCP-1 overexpression does not affect whole-body insulin sensitivity in mice.

Evers-van Gogh IJ, Oteng AB, Alex S, Hamers N, Catoire M, Stienstra R, Kalkhoven E, Kersten S. Evers-van Gogh IJ, et al. Among authors: hamers n. Diabetologia. 2016 Mar;59(3):624-33. doi: 10.1007/s00125-015-3822-2. Epub 2015 Dec 12. Diabetologia. 2016. PMID: 26661101 Free PMC article.

10

A Patient with Congenital Generalized Lipodystrophy Due To a Novel Mutation in BSCL2: Indications for Secondary Mitochondrial Dysfunction.

Jeninga EH, de Vroede M, Hamers N, Breur JM, Verhoeven-Duif NM, Berger R, Kalkhoven E. Jeninga EH, et al. Among authors: hamers n. JIMD Rep. 2012;4:47-54. doi: 10.1007/8904_2011_86. Epub 2011 Nov 4. JIMD Rep. 2012. PMID: 23430896 Free PMC article.

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