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The debranching enzyme Dbr1 regulates lariat turnover and intron splicing.
Buerer L, Clark NE, Welch A, Duan C, Taggart AJ, Townley BA, Wang J, Soemedi R, Rong S, Lin CL, Zeng Y, Katolik A, Staley JP, Damha MJ, Mosammaparast N, Fairbrother WG. Buerer L, et al. Among authors: staley jp. Nat Commun. 2024 May 30;15(1):4617. doi: 10.1038/s41467-024-48696-1. Nat Commun. 2024. PMID: 38816363 Free PMC article.
Global impact of unproductive splicing on human gene expression.
Fair B, Buen Abad Najar CF, Zhao J, Lozano S, Reilly A, Mossian G, Staley JP, Wang J, Li YI. Fair B, et al. Among authors: staley jp. Nat Genet. 2024 Sep;56(9):1851-1861. doi: 10.1038/s41588-024-01872-x. Epub 2024 Sep 2. Nat Genet. 2024. PMID: 39223315 Free PMC article.
Reverse transcriptases lend a hand in splicing catalysis.
Piccirilli JA, Staley JP. Piccirilli JA, et al. Among authors: staley jp. Nat Struct Mol Biol. 2016 Jun 7;23(6):507-9. doi: 10.1038/nsmb.3242. Nat Struct Mol Biol. 2016. PMID: 27273636 Free PMC article.
47 results