Chen PY - Search Results

1

Multiple Intravenous Bolus Dosing and Invasive Hemodynamic Assessment in a Hypoxia-Induced Mouse Pulmonary Artery Hypertension Model.

Qin L, Jiang B, Zsebo K, Duckers HJ, Simons M, Chen PY. Qin L, et al. Among authors: chen py. J Vis Exp. 2022 Nov 11;(189). doi: 10.3791/63839. J Vis Exp. 2022. PMID: 36440832

2

FRS2 via fibroblast growth factor receptor 1 is required for platelet-derived growth factor receptor beta-mediated regulation of vascular smooth muscle marker gene expression.

Chen PY, Simons M, Friesel R. Chen PY, et al. J Biol Chem. 2009 Jun 5;284(23):15980-92. doi: 10.1074/jbc.M809399200. Epub 2009 Apr 1. J Biol Chem. 2009. PMID: 19339244 Free PMC article.

3

FGF-dependent regulation of VEGF receptor 2 expression in mice.

Murakami M, Nguyen LT, Hatanaka K, Schachterle W, Chen PY, Zhuang ZW, Black BL, Simons M. Murakami M, et al. Among authors: chen py. J Clin Invest. 2011 Jul;121(7):2668-78. doi: 10.1172/JCI44762. J Clin Invest. 2011. PMID: 21633168 Free PMC article.

4

FGF regulates TGF-β signaling and endothelial-to-mesenchymal transition via control of let-7 miRNA expression.

Chen PY, Qin L, Barnes C, Charisse K, Yi T, Zhang X, Ali R, Medina PP, Yu J, Slack FJ, Anderson DG, Kotelianski V, Wang F, Tellides G, Simons M. Chen PY, et al. Cell Rep. 2012 Dec 27;2(6):1684-96. doi: 10.1016/j.celrep.2012.10.021. Epub 2012 Nov 29. Cell Rep. 2012. PMID: 23200853 Free PMC article.

5

The docking protein FRS2α is a critical regulator of VEGF receptors signaling.

Chen PY, Qin L, Zhuang ZW, Tellides G, Lax I, Schlessinger J, Simons M. Chen PY, et al. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5514-9. doi: 10.1073/pnas.1404545111. Epub 2014 Apr 2. Proc Natl Acad Sci U S A. 2014. PMID: 24706887 Free PMC article.

6

Fibroblast growth factor receptor 1 is a key inhibitor of TGFβ signaling in the endothelium.

Chen PY, Qin L, Tellides G, Simons M. Chen PY, et al. Sci Signal. 2014 Sep 23;7(344):ra90. doi: 10.1126/scisignal.2005504. Sci Signal. 2014. PMID: 25249657

7

Endothelial-to-mesenchymal transition drives atherosclerosis progression.

Chen PY, Qin L, Baeyens N, Li G, Afolabi T, Budatha M, Tellides G, Schwartz MA, Simons M. Chen PY, et al. J Clin Invest. 2015 Oct 26;125(12):4514-28. doi: 10.1172/JCI82719. J Clin Invest. 2015. PMID: 26517696 Free PMC article.

8

When endothelial cells go rogue.

Chen PY, Simons M. Chen PY, et al. EMBO Mol Med. 2016 Jan 1;8(1):1-2. doi: 10.15252/emmm.201505943. EMBO Mol Med. 2016. PMID: 26613939 Free PMC article.

9

Future Targets in Endothelial Biology: Endothelial Cell to Mesenchymal Transition.

Chen PY, Simons M. Chen PY, et al. Curr Drug Targets. 2016;17(15):1707-1713. doi: 10.2174/1389450117666160502151308. Curr Drug Targets. 2016. PMID: 27138761 Review.

10

Smooth muscle FGF/TGFβ cross talk regulates atherosclerosis progression.

Chen PY, Qin L, Li G, Tellides G, Simons M. Chen PY, et al. EMBO Mol Med. 2016 Jul 1;8(7):712-28. doi: 10.15252/emmm.201506181. Print 2016 Jul. EMBO Mol Med. 2016. PMID: 27189169 Free PMC article.

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