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The SARS-CoV-2 spike protein binds and modulates estrogen receptors.
Solis O, Beccari AR, Iaconis D, Talarico C, Ruiz-Bedoya CA, Nwachukwu JC, Cimini A, Castelli V, Bertini R, Montopoli M, Cocetta V, Borocci S, Prandi IG, Flavahan K, Bahr M, Napiorkowski A, Chillemi G, Ooka M, Yang X, Zhang S, Xia M, Zheng W, Bonaventura J, Pomper MG, Hooper JE, Morales M, Rosenberg AZ, Nettles KW, Jain SK, Allegretti M, Michaelides M. Solis O, et al. Among authors: xia m. Sci Adv. 2022 Dec 2;8(48):eadd4150. doi: 10.1126/sciadv.add4150. Epub 2022 Nov 30. Sci Adv. 2022. PMID: 36449624 Free PMC article.
Identification of HDAC Inhibitors Using a Cell-Based HDAC I/II Assay.
Hsu CW, Shou D, Huang R, Khuc T, Dai S, Zheng W, Klumpp-Thomas C, Xia M. Hsu CW, et al. Among authors: xia m. J Biomol Screen. 2016 Jul;21(6):643-52. doi: 10.1177/1087057116629381. Epub 2016 Feb 8. J Biomol Screen. 2016. PMID: 26858181 Free PMC article.
Biological activity-based modeling identifies antiviral leads against SARS-CoV-2.
Huang R, Xu M, Zhu H, Chen CZ, Zhu W, Lee EM, He S, Zhang L, Zhao J, Shamim K, Bougie D, Huang W, Xia M, Hall MD, Lo D, Simeonov A, Austin CP, Qiu X, Tang H, Zheng W. Huang R, et al. Among authors: xia m. Nat Biotechnol. 2021 Jun;39(6):747-753. doi: 10.1038/s41587-021-00839-1. Epub 2021 Feb 23. Nat Biotechnol. 2021. PMID: 33623157 Free PMC article.
Repurposing drugs as COVID-19 therapies: A toxicity evaluation.
Ngan DK, Xu T, Xia M, Zheng W, Huang R. Ngan DK, et al. Among authors: xia m. Drug Discov Today. 2022 Jul;27(7):1983-1993. doi: 10.1016/j.drudis.2022.04.001. Epub 2022 Apr 6. Drug Discov Today. 2022. PMID: 35395401 Free PMC article. Review.
3,665 results