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Noncanonical TGF-β signaling leads to FBXO3-mediated degradation of ΔNp63α promoting breast cancer metastasis and poor clinical prognosis.
Niu M, He Y, Xu J, Ding L, He T, Yi Y, Fu M, Guo R, Li F, Chen H, Chen YG, Xiao ZJ. Niu M, et al. Among authors: yi y. PLoS Biol. 2021 Feb 24;19(2):e3001113. doi: 10.1371/journal.pbio.3001113. eCollection 2021 Feb. PLoS Biol. 2021. Retraction in: PLoS Biol. 2024 Jun 27;22(6):e3002708. doi: 10.1371/journal.pbio.3002708 PMID: 33626035 Free PMC article. Retracted.
FBXL2 counteracts Grp94 to destabilize EGFR and inhibit EGFR-driven NSCLC growth.
Niu M, Xu J, Liu Y, Li Y, He T, Ding L, He Y, Yi Y, Li F, Guo R, Gao Y, Li R, Li L, Fu M, Hu Q, Luo Y, Zhang C, Qin K, Yi J, Yu S, Yang J, Chen H, Wang L, Li Z, Dong B, Qi S, Ouyang L, Zhang Y, Cao Y, Xiao ZJ. Niu M, et al. Among authors: yi y, yi j. Nat Commun. 2021 Oct 11;12(1):5919. doi: 10.1038/s41467-021-26222-x. Nat Commun. 2021. PMID: 34635651 Free PMC article.
4,728 results