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Page 1
OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases.
Sturm G, Karan KR, Monzel AS, Santhanam B, Taivassalo T, Bris C, Ware SA, Cross M, Towheed A, Higgins-Chen A, McManus MJ, Cardenas A, Lin J, Epel ES, Rahman S, Vissing J, Grassi B, Levine M, Horvath S, Haller RG, Lenaers G, Wallace DC, St-Onge MP, Tavazoie S, Procaccio V, Kaufman BA, Seifert EL, Hirano M, Picard M. Sturm G, et al. Among authors: santhanam b. Commun Biol. 2023 Jan 12;6(1):22. doi: 10.1038/s42003-022-04303-x. Commun Biol. 2023. PMID: 36635485 Free PMC article.
Cellular allostatic load is linked to increased energy expenditure and accelerated biological aging.
Bobba-Alves N, Sturm G, Lin J, Ware SA, Karan KR, Monzel AS, Bris C, Procaccio V, Lenaers G, Higgins-Chen A, Levine M, Horvath S, Santhanam BS, Kaufman BA, Hirano M, Epel E, Picard M. Bobba-Alves N, et al. Among authors: santhanam bs. Psychoneuroendocrinology. 2023 Sep;155:106322. doi: 10.1016/j.psyneuen.2023.106322. Epub 2023 Jun 14. Psychoneuroendocrinology. 2023. PMID: 37423094 Free PMC article.
A molecular switch from tumor suppressor to oncogene in ER+ve breast cancer: Role of androgen receptor, JAK-STAT, and lineage plasticity.
Asemota S, Effah W, Holt J, Johnson D, Cripe L, Ponnusamy S, Thiyagarajan T, Khosrosereshki Y, Hwang DJ, He Y, Grimes B, Fleming MD, Pritchard FE, Hendrix A, Fan M, Jain A, Choi HY, Makowski L, Hayes DN, Miller DD, Pfeffer LM, Santhanam B, Narayanan R. Asemota S, et al. Among authors: santhanam b. Proc Natl Acad Sci U S A. 2024 Oct;121(40):e2406837121. doi: 10.1073/pnas.2406837121. Epub 2024 Sep 23. Proc Natl Acad Sci U S A. 2024. PMID: 39312663
Dynamic conformational changes of a tardigrade group-3 late embryogenesis abundant protein modulate membrane biophysical properties.
Li XH, Yu CWH, Gomez-Navarro N, Stancheva V, Zhu H, Murthy A, Wozny M, Malhotra K, Johnson CM, Blackledge M, Santhanam B, Liu W, Huang J, Freund SMV, Miller EA, Babu MM. Li XH, et al. Among authors: santhanam b. PNAS Nexus. 2024 Jan 18;3(1):pgae006. doi: 10.1093/pnasnexus/pgae006. eCollection 2024 Jan. PNAS Nexus. 2024. PMID: 38269070 Free PMC article.
Ubiquitylation of lipopolysaccharide by RNF213 during bacterial infection.
Otten EG, Werner E, Crespillo-Casado A, Boyle KB, Dharamdasani V, Pathe C, Santhanam B, Randow F. Otten EG, et al. Among authors: santhanam b. Nature. 2021 Jun;594(7861):111-116. doi: 10.1038/s41586-021-03566-4. Epub 2021 May 19. Nature. 2021. PMID: 34012115 Free PMC article.
46 results