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Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical Candidates.
Mandal M, Xiao L, Pan W, Scapin G, Li G, Tang H, Yang SW, Pan J, Root Y, de Jesus RK, Yang C, Prosise W, Dayananth P, Mirza A, Therien AG, Young K, Flattery A, Garlisi C, Zhang R, Chu D, Sheth P, Chu I, Wu J, Markgraf C, Kim HY, Painter R, Mayhood TW, DiNunzio E, Wyss DF, Buevich AV, Fischmann T, Pasternak A, Dong S, Hicks JD, Villafania A, Liang L, Murgolo N, Black T, Hagmann WK, Tata J, Parmee ER, Weber AE, Su J, Tang H. Mandal M, et al. Among authors: black t. J Med Chem. 2022 Dec 22;65(24):16234-16251. doi: 10.1021/acs.jmedchem.2c00766. Epub 2022 Dec 7. J Med Chem. 2022. PMID: 36475645
Structure Guided Discovery of Novel Pan Metallo-β-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration.
Dong S, Zhao Z, Tang H, Li G, Pan J, Gu X, Jiang J, Xiao L, Scapin G, Hunter DN, Yang D, Huang Y, Bennett F, Yang SW, Mandal M, Tang H, Su J, Tudge C, deJesus RK, Ding FX, Lombardo M, Hicks JD, Fischmann T, Mirza A, Dayananth P, Painter RE, Villafania A, Garlisi CG, Zhang R, Mayhood TW, Si Q, Li N, Amin RP, Bhatt B, Chen F, Regan CP, Regan H, Lin X, Wu J, Leithead A, Pollack SR, Scott JD, Nargund RP, Therien AG, Black T, Young K, Pasternak A. Dong S, et al. Among authors: black t. J Med Chem. 2024 Mar 14;67(5):3400-3418. doi: 10.1021/acs.jmedchem.3c01614. Epub 2024 Feb 22. J Med Chem. 2024. PMID: 38387069
Cerastecins inhibit membrane lipooligosaccharide transport in drug-resistant Acinetobacter baumannii.
Wang H, Ishchenko A, Skudlarek J, Shen P, Dzhekieva L, Painter RE, Chen YT, Bukhtiyarova M, Leithead A, Tracy R, Babaoglu K, Bahnck-Teets C, Buevich A, Cabalu TD, Labroli M, Lange H, Lei Y, Li W, Liu J, Mann PA, Meng T, Mitchell HJ, Mulhearn J, Scapin G, Sha D, Shaw AW, Si Q, Tong L, Wu C, Wu Z, Xiao JC, Xu M, Zhang LK, McKenney D, Miller RR, Black TA, Cooke A, Balibar CJ, Klein DJ, Raheem I, Walker SS. Wang H, et al. Among authors: black ta. Nat Microbiol. 2024 May;9(5):1244-1255. doi: 10.1038/s41564-024-01667-0. Epub 2024 Apr 22. Nat Microbiol. 2024. PMID: 38649414
Differential effects of gestational Cannabis smoke and phytocannabinoid injections on male and female rat offspring behavior.
Black T, Barnard IL, Baccetto SL, Greba Q, Orvold SN, Austin-Scott FVL, Sanfuego GB, Onofrychuk TJ, Glass AE, Andres RM, Macfarlane LM, Adrian JC, Heidt AL, McElroy DL, Laprairie RB, Howland JG. Black T, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2025 Jan 5:111241. doi: 10.1016/j.pnpbp.2024.111241. Online ahead of print. Prog Neuropsychopharmacol Biol Psychiatry. 2025. PMID: 39765319 Free article.
Nursing Wellness in Academic and Clinical Cardiovascular and Stroke Nursing: A Scientific Statement From the American Heart Association.
Pike NA, Dougherty CM, Black T, Freedenberg V, Green TL, Howie-Esquivel J, Pucciarelli G, Souffront K, St Laurent P; American Heart Association Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; and Council on Lifestyle and Cardiometabolic Health. Pike NA, et al. Among authors: black t. J Am Heart Assoc. 2025 Jan 7;14(1):e038199. doi: 10.1161/JAHA.124.038199. Epub 2024 Dec 18. J Am Heart Assoc. 2025. PMID: 39692032 Free article.
Contribution of telacebec to novel drug regimens in a murine tuberculosis model.
Komm OD, Tyagi S, Garcia A, Almeida D, Chang Y, Li S-Y, Castillo JR, Converse PJ, Black T, Fotouhi N, Nuermberger EL. Komm OD, et al. Among authors: black t. Antimicrob Agents Chemother. 2024 Dec 9:e0096224. doi: 10.1128/aac.00962-24. Online ahead of print. Antimicrob Agents Chemother. 2024. PMID: 39651910 Free article.
489 results