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Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis.
Janneh AH, Kassir MF, Atilgan FC, Lee HG, Sheridan M, Oleinik N, Szulc Z, Voelkel-Johnson C, Nguyen H, Li H, Peterson YK, Marangoni E, Saatci O, Sahin O, Lilly M, Atkinson C, Tomlinson S, Mehrotra S, Ogretmen B. Janneh AH, et al. Among authors: mehrotra s. Cell Rep. 2022 Dec 6;41(10):111742. doi: 10.1016/j.celrep.2022.111742. Cell Rep. 2022. PMID: 36476873 Free PMC article.
Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance.
Gao X, Wu Y, Chick JM, Abbott A, Jiang B, Wang DJ, Comte-Walters S, Johnson RH, Oberholtzer N, Nishimura MI, Gygi SP, Mehta A, Guttridge DC, Ball L, Mehrotra S, Sicinski P, Yu XZ, Wang H. Gao X, et al. Among authors: mehrotra s. Cell Rep. 2023 Apr 25;42(4):112314. doi: 10.1016/j.celrep.2023.112314. Epub 2023 Mar 30. Cell Rep. 2023. PMID: 37000627 Free PMC article.
Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response.
Wofford W, Kim J, Kim D, Janneh AH, Lee HG, Atilgan FC, Oleinik N, Kassir MF, Saatci O, Chakraborty P, Tokat UM, Gencer S, Howley B, Howe P, Mehrotra S, Sahin O, Ogretmen B. Wofford W, et al. Among authors: mehrotra s. Cell Rep. 2024 Aug 27;43(8):114532. doi: 10.1016/j.celrep.2024.114532. Epub 2024 Jul 23. Cell Rep. 2024. PMID: 39046874 Free PMC article.
Microsomal glutathione transferase 1 controls metastasis and therapeutic response in melanoma.
Zhang J, Ye ZW, Chakraborty P, Luo Z, Culpepper J, Aslam M, Zhang L, Johansson K, Haeggström JZ, Xu J, Olsson M, Townsend DM, Mehrotra S, Morgenstern R, Tew KD. Zhang J, et al. Among authors: mehrotra s. Pharmacol Res. 2023 Oct;196:106899. doi: 10.1016/j.phrs.2023.106899. Epub 2023 Aug 28. Pharmacol Res. 2023. PMID: 37648102 Free PMC article.
A role for microsomal glutathione transferase 1 in melanin biosynthesis and melanoma progression.
Zhang J, Ye ZW, Bräutigam L, Chakraborty P, Luo Z, Culpepper J, Aslam M, Zhang L, Johansson K, Haeggström JZ, Xu J, Olsson M, Townsend DM, Mehrotra S, Morgenstern R, Tew KD. Zhang J, et al. Among authors: mehrotra s. J Biol Chem. 2023 Aug;299(8):104920. doi: 10.1016/j.jbc.2023.104920. Epub 2023 Jun 14. J Biol Chem. 2023. PMID: 37321450 Free PMC article.
CD38-RyR2 axis-mediated signaling impedes CD8+ T cell response to anti-PD1 therapy in cancer.
Kar A, Ghosh P, Gautam A, Chowdhury S, Basak D, Sarkar I, Bhoumik A, Barman S, Chakraborty P, Mukhopadhyay A, Mehrotra S, Ganesan SK, Paul S, Chatterjee S. Kar A, et al. Among authors: mehrotra s. Proc Natl Acad Sci U S A. 2024 Mar 12;121(11):e2315989121. doi: 10.1073/pnas.2315989121. Epub 2024 Mar 7. Proc Natl Acad Sci U S A. 2024. PMID: 38451948 Free PMC article.
Cabozantinib inhibits tumor growth in mice with ovarian cancer.
Stiff PJ, Kertowidjojo E, Potkul RK, Banerjee S, Mehrotra S, Small W Jr, Stack MS, Drakes ML. Stiff PJ, et al. Among authors: mehrotra s. Am J Cancer Res. 2024 Oct 15;14(10):4788-4802. doi: 10.62347/ZSWV1767. eCollection 2024. Am J Cancer Res. 2024. PMID: 39553221 Free PMC article.
862 results