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A Phase 2A Trial of the Safety and Tolerability of Increased Dose Rifampicin and Adjunctive Linezolid, With or Without Aspirin, for Human Immunodeficiency Virus-Associated Tuberculous Meningitis: The LASER-TBM Trial.
Davis AG, Wasserman S, Stek C, Maxebengula M, Jason Liang C, Stegmann S, Koekemoer S, Jackson A, Kadernani Y, Bremer M, Daroowala R, Aziz S, Goliath R, Lai Sai L, Sihoyiya T, Denti P, Lai RPJ, Crede T, Naude J, Szymanski P, Vallie Y, Banderker IA, Moosa MS, Raubenheimer P, Candy S, Offiah C, Wahl G, Vorster I, Maartens G, Black J, Meintjes G, Wilkinson RJ. Davis AG, et al. Among authors: lai rpj. Clin Infect Dis. 2023 Apr 17;76(8):1412-1422. doi: 10.1093/cid/ciac932. Clin Infect Dis. 2023. PMID: 36482216 Free PMC article. Clinical Trial.
HIV-tuberculosis-associated immune reconstitution inflammatory syndrome is characterized by Toll-like receptor and inflammasome signalling.
Lai RPJ, Meintjes G, Wilkinson KA, Graham CM, Marais S, Van der Plas H, Deffur A, Schutz C, Bloom C, Munagala I, Anguiano E, Goliath R, Maartens G, Banchereau J, Chaussabel D, O'Garra A, Wilkinson RJ. Lai RPJ, et al. Nat Commun. 2015 Sep 24;6:8451. doi: 10.1038/ncomms9451. Nat Commun. 2015. PMID: 26399326 Free PMC article.
Corticosteroids as an adjunct to tuberculosis therapy.
Schutz C, Davis AG, Sossen B, Lai RP, Ntsekhe M, Harley YX, Wilkinson RJ. Schutz C, et al. Expert Rev Respir Med. 2018 Oct;12(10):881-891. doi: 10.1080/17476348.2018.1515628. Epub 2018 Sep 6. Expert Rev Respir Med. 2018. PMID: 30138039 Free PMC article. Review.
Tuberculous meningitis: new tools and new approaches required.
Seddon JA, Thwaites GE; Tuberculous Meningitis International Research Consortium. Seddon JA, et al. Wellcome Open Res. 2019 Nov 19;4:181. doi: 10.12688/wellcomeopenres.15591.1. eCollection 2019. Wellcome Open Res. 2019. PMID: 31803849 Free PMC article.
Management of intracranial tuberculous mass lesions: how long should we treat for?
Marais S, Van Toorn R, Chow FC, Manesh A, Siddiqi OK, Figaji A, Schoeman JF, Meintjes G; Tuberculous Meningitis International Research Consortium. Marais S, et al. Wellcome Open Res. 2019 Oct 31;4:158. doi: 10.12688/wellcomeopenres.15501.2. eCollection 2019. Wellcome Open Res. 2019. PMID: 32047859 Free PMC article.
28 results