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3,5,7-Substituted Pyrazolo[4,3- d]pyrimidine Inhibitors of Cyclin-Dependent Kinases and Their Evaluation in Lymphoma Models.
Jorda R, Havlíček L, Šturc A, Tušková D, Daumová L, Alam M, Škerlová J, Nekardová M, Peřina M, Pospíšil T, Široká J, Urbánek L, Pachl P, Řezáčová P, Strnad M, Klener P, Kryštof V. Jorda R, et al. Among authors: perina m. J Med Chem. 2019 May 9;62(9):4606-4623. doi: 10.1021/acs.jmedchem.9b00189. Epub 2019 Apr 17. J Med Chem. 2019. PMID: 30943029
3H-Pyrazolo[4,3-f]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo.
Dayal N, Řezníčková E, Hernandez DE, Peřina M, Torregrosa-Allen S, Elzey BD, Škerlová J, Ajani H, Djukic S, Vojáčková V, Lepšík M, Řezáčová P, Kryštof V, Jorda R, Sintim HO. Dayal N, et al. Among authors: perina m. J Med Chem. 2021 Aug 12;64(15):10981-10996. doi: 10.1021/acs.jmedchem.1c00330. Epub 2021 Jul 21. J Med Chem. 2021. PMID: 34288692
Characterization of new highly selective pyrazolo[4,3-d]pyrimidine inhibitor of CDK7.
Kovalová M, Havlíček L, Djukic S, Škerlová J, Peřina M, Pospíšil T, Řezníčková E, Řezáčová P, Jorda R, Kryštof V. Kovalová M, et al. Among authors: perina m. Biomed Pharmacother. 2023 May;161:114492. doi: 10.1016/j.biopha.2023.114492. Epub 2023 Mar 15. Biomed Pharmacother. 2023. PMID: 36931035 Free article.
Identification of furo[2,3-d]pyrimidin-4-ylsulfanyl-1,3,4-thiadiazole derivatives as novel FLT3-ITD inhibitors.
Moradi M, Mousavi A, Řezníčková E, Peytam F, Peřina M, Vojáčková V, Firoozpour L, Jorda R, Grúz J, Emamgholipour Z, Sadat-Ebrahimi SE, Kryštof V, Foroumadi A. Moradi M, et al. Among authors: perina m. Eur J Med Chem. 2024 Dec 15;280:116962. doi: 10.1016/j.ejmech.2024.116962. Epub 2024 Oct 12. Eur J Med Chem. 2024. PMID: 39427515 Free article.
35 results