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Optical and radioiodinated tethered Hsp90 inhibitors reveal selective internalization of ectopic Hsp90 in malignant breast tumor cells.
Barrott JJ, Hughes PF, Osada T, Yang XY, Hartman ZC, Loiselle DR, Spector NL, Neckers L, Rajaram N, Hu F, Ramanujam N, Vaidyanathan G, Zalutsky MR, Lyerly HK, Haystead TA. Barrott JJ, et al. Among authors: osada t. Chem Biol. 2013 Sep 19;20(9):1187-97. doi: 10.1016/j.chembiol.2013.08.004. Epub 2013 Sep 12. Chem Biol. 2013. PMID: 24035283 Free PMC article.
HSP90-Specific nIR Probe Identifies Aggressive Prostate Cancers: Translation from Preclinical Models to a Human Phase I Study.
Osada T, Crosby EJ, Kaneko K, Snyder JC, Ginzel JD, Acharya CR, Yang XY, Polascik TJ, Spasojevic I, Nelson RC, Hobeika A, Hartman ZC, Neckers LM, Rogatko A, Hughes PF, Huang J, Morse MA, Haystead T, Lyerly HK. Osada T, et al. Mol Cancer Ther. 2022 Jan;21(1):217-226. doi: 10.1158/1535-7163.MCT-21-0334. Epub 2021 Oct 21. Mol Cancer Ther. 2022. PMID: 34675120 Free PMC article. Clinical Trial.
Combination of a novel heat shock protein 90-targeted photodynamic therapy with PD-1/PD-L1 blockade induces potent systemic antitumor efficacy and abscopal effect against breast cancers.
Kaneko K, Acharya CR, Nagata H, Yang X, Hartman ZC, Hobeika A, Hughes PF, Haystead TAJ, Morse MA, Lyerly HK, Osada T. Kaneko K, et al. Among authors: osada t. J Immunother Cancer. 2022 Sep;10(9):e004793. doi: 10.1136/jitc-2022-004793. J Immunother Cancer. 2022. PMID: 36171008 Free PMC article.
Immunotherapeutic targeting of Wilms' tumor protein.
Hutchings Y, Osada T, Woo CY, Clay TM, Lyerly HK, Morse MA. Hutchings Y, et al. Among authors: osada t. Curr Opin Mol Ther. 2007 Feb;9(1):62-9. Curr Opin Mol Ther. 2007. PMID: 17330403 Review.
761 results