Kumagai Y - Search Results

1

Alterations in UPR Signaling by Methylmercury Trigger Neuronal Cell Death in the Mouse Brain.

Nomura R, Takasugi N, Hiraoka H, Iijima Y, Iwawaki T, Kumagai Y, Fujimura M, Uehara T. Nomura R, et al. Among authors: kumagai y. Int J Mol Sci. 2022 Dec 6;23(23):15412. doi: 10.3390/ijms232315412. Int J Mol Sci. 2022. PMID: 36499738 Free PMC article.

2

DNA microarray analysis of human neuroblastoma SH-SY5Y cells exposed to methylmercury.

Toyama T, Yoshida E, Shinkai Y, Kumagai Y. Toyama T, et al. Among authors: kumagai y. J Toxicol Sci. 2011;36(6):843-5. doi: 10.2131/jts.36.843. J Toxicol Sci. 2011. PMID: 22129749 Free article.

3

The role of the Keap1/Nrf2 pathway in the cellular response to methylmercury.

Kumagai Y, Kanda H, Shinkai Y, Toyama T. Kumagai Y, et al. Oxid Med Cell Longev. 2013;2013:848279. doi: 10.1155/2013/848279. Epub 2013 Jun 26. Oxid Med Cell Longev. 2013. PMID: 23878621 Free PMC article. Review.

4

S-mercuration of cellular proteins by methylmercury and its toxicological implications.

Kanda H, Shinkai Y, Kumagai Y. Kanda H, et al. Among authors: kumagai y. J Toxicol Sci. 2014;39(5):687-700. doi: 10.2131/jts.39.687. J Toxicol Sci. 2014. PMID: 25242398 Free article. Review.

5

Correlation between attenuation of protein disulfide isomerase activity through S-mercuration and neurotoxicity induced by methylmercury.

Makino K, Okuda K, Sugino E, Nishiya T, Toyama T, Iwawaki T, Fujimura M, Kumagai Y, Uehara T. Makino K, et al. Among authors: kumagai y. Neurotox Res. 2015 Feb;27(2):99-105. doi: 10.1007/s12640-014-9494-8. Epub 2014 Oct 7. Neurotox Res. 2015. PMID: 25288108

6

S-Mercuration of ubiquitin carboxyl-terminal hydrolase L1 through Cys152 by methylmercury causes inhibition of its catalytic activity and reduction of monoubiquitin levels in SH-SY5Y cells.

Toyama T, Abiko Y, Katayama Y, Kaji T, Kumagai Y. Toyama T, et al. Among authors: kumagai y. J Toxicol Sci. 2015 Dec;40(6):887-93. doi: 10.2131/jts.40.887. J Toxicol Sci. 2015. PMID: 26558469 Free article.

7

Methylmercury, an environmental electrophile capable of activation and disruption of the Akt/CREB/Bcl-2 signal transduction pathway in SH-SY5Y cells.

Unoki T, Abiko Y, Toyama T, Uehara T, Tsuboi K, Nishida M, Kaji T, Kumagai Y. Unoki T, et al. Among authors: kumagai y. Sci Rep. 2016 Jun 30;6:28944. doi: 10.1038/srep28944. Sci Rep. 2016. PMID: 27357941 Free PMC article.

8

Polysulfide Na₂S₄ regulates the activation of PTEN/Akt/CREB signaling and cytotoxicity mediated by 1,4-naphthoquinone through formation of sulfur adducts.

Abiko Y, Shinkai Y, Unoki T, Hirose R, Uehara T, Kumagai Y. Abiko Y, et al. Among authors: kumagai y. Sci Rep. 2017 Jul 6;7(1):4814. doi: 10.1038/s41598-017-04590-z. Sci Rep. 2017. PMID: 28684787 Free PMC article.

9

Modulation of Unfolded Protein Response by Methylmercury.

Hiraoka H, Nakahara K, Kaneko Y, Akiyama S, Okuda K, Iwawaki T, Fujimura M, Kumagai Y, Takasugi N, Uehara T. Hiraoka H, et al. Among authors: kumagai y. Biol Pharm Bull. 2017;40(9):1595-1598. doi: 10.1248/bpb.b17-00359. Biol Pharm Bull. 2017. PMID: 28867746 Free article.

10

Nrf2 Activation and Its Coordination with the Protective Defense Systems in Response to Electrophilic Stress.

Unoki T, Akiyama M, Kumagai Y. Unoki T, et al. Among authors: kumagai y. Int J Mol Sci. 2020 Jan 15;21(2):545. doi: 10.3390/ijms21020545. Int J Mol Sci. 2020. PMID: 31952233 Free PMC article. Review.

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