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N-[1,3-Dialkyl(aryl)-2-oxoimidazolidin-4-ylidene]-aryl(alkyl)sulphonamides as Novel Selective Human Cannabinoid Type 2 Receptor (hCB2R) Ligands; Insights into the Mechanism of Receptor Activation/Deactivation.
Gianquinto E, Sodano F, Rolando B, Kostrzewa M, Allarà M, Mahmoud AM, Kumar P, Spyrakis F, Ligresti A, Chegaev K. Gianquinto E, et al. Among authors: spyrakis f. Molecules. 2022 Nov 23;27(23):8152. doi: 10.3390/molecules27238152. Molecules. 2022. PMID: 36500256 Free PMC article.
Target flexibility: an emerging consideration in drug discovery and design.
Cozzini P, Kellogg GE, Spyrakis F, Abraham DJ, Costantino G, Emerson A, Fanelli F, Gohlke H, Kuhn LA, Morris GM, Orozco M, Pertinhez TA, Rizzi M, Sotriffer CA. Cozzini P, et al. Among authors: spyrakis f. J Med Chem. 2008 Oct 23;51(20):6237-55. doi: 10.1021/jm800562d. Epub 2008 Sep 12. J Med Chem. 2008. PMID: 18785728 Free PMC article. No abstract available.
Chemogenomics of pyridoxal 5'-phosphate dependent enzymes.
Singh R, Spyrakis F, Cozzini P, Paiardini A, Pascarella S, Mozzarelli A. Singh R, et al. Among authors: spyrakis f. J Enzyme Inhib Med Chem. 2013 Feb;28(1):183-94. doi: 10.3109/14756366.2011.643305. Epub 2011 Dec 19. J Enzyme Inhib Med Chem. 2013. PMID: 22181815 Free article.
Strigolactones as Broad-Spectrum Antivirals against β-Coronaviruses through Targeting the Main Protease Mpro.
Biolatti M, Blangetti M, Baggieri M, Marchi A, Gioacchini S, Bajetto G, Arnodo D, Bucci P, Fioravanti R, Kojouri M, Bersani M, D'Arrigo G, Siragusa L, Ghinato S, De Andrea M, Gugliesi F, Albano C, Pasquero S, Visentin I, D'Ugo E, Esposito F, Malune P, Tramontano E, Prandi C, Spyrakis F, Magurano F, Dell'Oste V. Biolatti M, et al. Among authors: spyrakis f. ACS Infect Dis. 2023 Jul 14;9(7):1310-1318. doi: 10.1021/acsinfecdis.3c00219. Epub 2023 Jun 26. ACS Infect Dis. 2023. PMID: 37358826
Ligand migration and hexacoordination in type 1 non-symbiotic rice hemoglobin.
Bisht NK, Abbruzzetti S, Uppal S, Bruno S, Spyrakis F, Mozzarelli A, Viappiani C, Kundu S. Bisht NK, et al. Among authors: spyrakis f. Biochim Biophys Acta. 2011 Aug;1814(8):1042-53. doi: 10.1016/j.bbapap.2010.09.016. Epub 2010 Oct 29. Biochim Biophys Acta. 2011. PMID: 20940062
117 results