Flint RB - Search Results

1

Oral Ibuprofen Is More Effective than Intravenous Ibuprofen for Closure of a Patent Ductus Arteriosus: Can Pharmacokinetic Modeling Help Us to Understand Why?

Smit C, Engbers AGJ, Samiee-Zafarghandy S, van Donge T, Simons SHP, Flint RB, Pfister M, Knibbe CAJ, van den Anker JN. Smit C, et al. Among authors: flint rb. Neonatology. 2023;120(1):81-89. doi: 10.1159/000526210. Epub 2022 Dec 9. Neonatology. 2023. PMID: 36502794 Free article.

2

Retrospective study shows that doxapram therapy avoided the need for endotracheal intubation in most premature neonates.

Flint R, Halbmeijer N, Meesters N, van Rosmalen J, Reiss I, van Dijk M, Simons S. Flint R, et al. Acta Paediatr. 2017 May;106(5):733-739. doi: 10.1111/apa.13761. Epub 2017 Mar 1. Acta Paediatr. 2017. PMID: 28130789

3

Model-based clinical dose optimization for phenobarbital in neonates: An illustration of the importance of data sharing and external validation.

Völler S, Flint RB, Stolk LM, Degraeuwe PLJ, Simons SHP, Pokorna P, Burger DM, de Groot R, Tibboel D, Knibbe CAJ; DINO study group. Völler S, et al. Among authors: flint rb. Eur J Pharm Sci. 2017 Nov 15;109S:S90-S97. doi: 10.1016/j.ejps.2017.05.026. Epub 2017 May 12. Eur J Pharm Sci. 2017. PMID: 28506869 Free article.

4

Exposure to acetaminophen and all its metabolites upon 10, 15, and 20 mg/kg intravenous acetaminophen in very-preterm infants.

Flint RB, Roofthooft DW, van Rongen A, van Lingen RA, van den Anker JN, van Dijk M, Allegaert K, Tibboel D, Knibbe CAJ, Simons SHP. Flint RB, et al. Pediatr Res. 2017 Oct;82(4):678-684. doi: 10.1038/pr.2017.129. Epub 2017 Jun 21. Pediatr Res. 2017. PMID: 28553988 Clinical Trial.

5

Big Data Analyses for Continuous Evaluation of Pharmacotherapy: A Proof of Principle with Doxapram in Preterm Infants.

Flint RB, Weteringen WV, Voller S, Poppe JA, Koch BCP, de Groot R, Tibboel D, Knibbe CAJ, Reiss IKM, Simons SHP, Dino Research Group. Flint RB, et al. Curr Pharm Des. 2017;23(38):5919-5927. doi: 10.2174/1381612823666170918121556. Curr Pharm Des. 2017. PMID: 28925893

6

Large differences in neonatal drug use between NICUs are common practice: time for consensus?

Flint RB, van Beek F, Andriessen P, Zimmermann LJ, Liem KD, Reiss IKM, de Groot R, Tibboel D, Burger DM, Simons SHP; DINO Research group. Flint RB, et al. Br J Clin Pharmacol. 2018 Jun;84(6):1313-1323. doi: 10.1111/bcp.13563. Epub 2018 Apr 17. Br J Clin Pharmacol. 2018. PMID: 29624207 Free PMC article.

7

Simulation-based suggestions to improve ibuprofen dosing for patent ductus arteriosus in preterm newborns.

Flint RB, Ter Heine R, Spaans E, Burger DM, de Klerk JCA, Allegaert K, Knibbe CAJ, Simons SHP. Flint RB, et al. Eur J Clin Pharmacol. 2018 Dec;74(12):1585-1591. doi: 10.1007/s00228-018-2529-y. Epub 2018 Jul 28. Eur J Clin Pharmacol. 2018. PMID: 30054639 Free PMC article.

8

Recently Registered Midazolam Doses for Preterm Neonates Do Not Lead to Equal Exposure: A Population Pharmacokinetic Model.

Völler S, Flint RB, Beggah F, Reiss I, Andriessen P, Zimmermann LJI, van den Anker JN, Liem KD, Koch BCP, de Wildt S, Knibbe CAJ, Simons SHP. Völler S, et al. Among authors: flint rb. J Clin Pharmacol. 2019 Oct;59(10):1300-1308. doi: 10.1002/jcph.1429. Epub 2019 May 15. J Clin Pharmacol. 2019. PMID: 31093992 Free PMC article. Clinical Trial.

9

Rapidly maturing fentanyl clearance in preterm neonates.

Völler S, Flint RB, Andriessen P, Allegaert K, Zimmermann LJI, Liem KD, Koch BCP, Simons SHP, Knibbe CAJ; DINO study group. Völler S, et al. Among authors: flint rb. Arch Dis Child Fetal Neonatal Ed. 2019 Nov;104(6):F598-F603. doi: 10.1136/archdischild-2018-315920. Epub 2019 Feb 1. Arch Dis Child Fetal Neonatal Ed. 2019. PMID: 31498775

10

Ibuprofen treatment after the first days of life in preterm neonates with patent ductus arteriosus.

de Klerk JCA, van Paassen N, van Beynum IM, Flint RB, Reiss IKM, Simons SHP. de Klerk JCA, et al. Among authors: flint rb. J Matern Fetal Neonatal Med. 2021 Aug;34(15):2411-2417. doi: 10.1080/14767058.2019.1667323. Epub 2019 Sep 23. J Matern Fetal Neonatal Med. 2021. PMID: 31510826 Free article.

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