Joosten AM - Search Results

1

Tolerogenic dendritic cells pulsed with islet antigen induce long-term reduction in T-cell autoreactivity in type 1 diabetes patients.

Nikolic T, Suwandi JS, Wesselius J, Laban S, Joosten AM, Sonneveld P, Mul D, Aanstoot HJ, Kaddis JS, Zwaginga JJ, Roep BO. Nikolic T, et al. Among authors: joosten am. Front Immunol. 2022 Nov 23;13:1054968. doi: 10.3389/fimmu.2022.1054968. eCollection 2022. Front Immunol. 2022. PMID: 36505460 Free PMC article. Clinical Trial.

2

Critical role for TNF in the induction of human antigen-specific regulatory T cells by tolerogenic dendritic cells.

Kleijwegt FS, Laban S, Duinkerken G, Joosten AM, Zaldumbide A, Nikolic T, Roep BO. Kleijwegt FS, et al. Among authors: joosten am. J Immunol. 2010 Aug 1;185(3):1412-8. doi: 10.4049/jimmunol.1000560. Epub 2010 Jun 23. J Immunol. 2010. PMID: 20574005

3

Transfer of regulatory properties from tolerogenic to proinflammatory dendritic cells via induced autoreactive regulatory T cells.

Kleijwegt FS, Laban S, Duinkerken G, Joosten AM, Koeleman BP, Nikolic T, Roep BO. Kleijwegt FS, et al. Among authors: joosten am. J Immunol. 2011 Dec 15;187(12):6357-64. doi: 10.4049/jimmunol.1101638. Epub 2011 Nov 14. J Immunol. 2011. PMID: 22084438

4

Tolerogenic dendritic cells impede priming of naïve CD8⁺ T cells and deplete memory CD8⁺ T cells.

Kleijwegt FS, Jansen DT, Teeler J, Joosten AM, Laban S, Nikolic T, Roep BO. Kleijwegt FS, et al. Among authors: joosten am. Eur J Immunol. 2013 Jan;43(1):85-92. doi: 10.1002/eji.201242879. Epub 2012 Nov 12. Eur J Immunol. 2013. PMID: 23042025 Free article.

5

Dendritic Cells Guide Islet Autoimmunity through a Restricted and Uniquely Processed Peptidome Presented by High-Risk HLA-DR.

van Lummel M, van Veelen PA, de Ru AH, Janssen GM, Pool J, Laban S, Joosten AM, Nikolic T, Drijfhout JW, Mearin ML, Aanstoot HJ, Peakman M, Roep BO. van Lummel M, et al. Among authors: joosten am. J Immunol. 2016 Apr 15;196(8):3253-63. doi: 10.4049/jimmunol.1501282. Epub 2016 Mar 4. J Immunol. 2016. PMID: 26944932

6

Differential transcriptome of tolerogenic versus inflammatory dendritic cells points to modulated T1D genetic risk and enriched immune regulation.

Nikolic T, Woittiez NJC, van der Slik A, Laban S, Joosten A, Gysemans C, Mathieu C, Zwaginga JJ, Koeleman B, Roep BO. Nikolic T, et al. Genes Immun. 2017 Sep;18(3):176-183. doi: 10.1038/gene.2017.18. Epub 2017 Aug 10. Genes Immun. 2017. PMID: 28794505

7

Multidimensional analyses of proinsulin peptide-specific regulatory T cells induced by tolerogenic dendritic cells.

Suwandi JS, Laban S, Vass K, Joosten A, van Unen V, Lelieveldt BPF, Höllt T, Zwaginga JJ, Nikolic T, Roep BO. Suwandi JS, et al. J Autoimmun. 2020 Feb;107:102361. doi: 10.1016/j.jaut.2019.102361. Epub 2019 Nov 24. J Autoimmun. 2020. PMID: 31776056 Free article.

8

1,25-dihydroxyvitamin D3 induces stable and reproducible therapeutic tolerogenic dendritic cells with specific epigenetic modifications.

van Megen KM, Chen Z, Joosten AM, Laban S, Zwaginga JJ, Natarajan R, Nikolic T, Roep BO. van Megen KM, et al. Among authors: joosten am. Cytotherapy. 2021 Mar;23(3):242-255. doi: 10.1016/j.jcyt.2020.12.003. Epub 2021 Jan 15. Cytotherapy. 2021. PMID: 33461863 Free PMC article.

9

Discovery of a Selective Islet Peptidome Presented by the Highest-Risk HLA-DQ8trans Molecule.

van Lummel M, van Veelen PA, de Ru AH, Pool J, Nikolic T, Laban S, Joosten A, Drijfhout JW, Gómez-Touriño I, Arif S, Aanstoot HJ, Peakman M, Roep BO. van Lummel M, et al. Diabetes. 2016 Mar;65(3):732-41. doi: 10.2337/db15-1031. Epub 2015 Dec 30. Diabetes. 2016. PMID: 26718497

10

Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes.

Kracht MJ, van Lummel M, Nikolic T, Joosten AM, Laban S, van der Slik AR, van Veelen PA, Carlotti F, de Koning EJ, Hoeben RC, Zaldumbide A, Roep BO. Kracht MJ, et al. Among authors: joosten am. Nat Med. 2017 Apr;23(4):501-507. doi: 10.1038/nm.4289. Epub 2017 Feb 27. Nat Med. 2017. PMID: 28263308

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