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The design of experiments (DoE) in optimization of an aerobic flow Pd-catalyzed oxidation of alcohol towards an important aldehyde precursor in the synthesis of phosphatidylinositide 3-kinase inhibitor (CPL302415).
Michałek S, Gurba-Bryśkiewicz L, Maruszak W, Zagozda M, Maj AM, Ochal Z, Dubiel K, Wieczorek M. Michałek S, et al. Among authors: zagozda m. RSC Adv. 2022 Nov 23;12(52):33605-33611. doi: 10.1039/d2ra07003k. eCollection 2022 Nov 22. RSC Adv. 2022. PMID: 36505705 Free PMC article.
Preclinical characterization of CPL302-253, a selective inhibitor of PI3Kδ, as the candidate for the inhalatory treatment and prevention of Asthma.
Gunerka P, Gala K, Banach M, Dominowski J, Hucz-Kalitowska J, Mulewski K, Hajnal A, Mikus EG, Smuga D, Zagozda M, Dubiel K, Pieczykolan J, Zygmunt BM, Wieczorek M. Gunerka P, et al. Among authors: zagozda m. PLoS One. 2020 Jul 23;15(7):e0236159. doi: 10.1371/journal.pone.0236159. eCollection 2020. PLoS One. 2020. PMID: 32702053 Free PMC article.
Design, Synthesis, and Development of Pyrazolo[1,5-a]pyrimidine Derivatives as a Novel Series of Selective PI3Kδ Inhibitors: Part II-Benzimidazole Derivatives.
Stypik M, Michałek S, Orłowska N, Zagozda M, Dziachan M, Banach M, Turowski P, Gunerka P, Zdżalik-Bielecka D, Stańczak A, Kędzierska U, Mulewski K, Smuga D, Maruszak W, Gurba-Bryśkiewicz L, Leniak A, Pietruś W, Ochal Z, Mach M, Zygmunt B, Pieczykolan J, Dubiel K, Wieczorek M. Stypik M, et al. Among authors: zagozda m. Pharmaceuticals (Basel). 2022 Jul 27;15(8):927. doi: 10.3390/ph15080927. Pharmaceuticals (Basel). 2022. PMID: 36015075 Free PMC article.
Design, Synthesis, and Development of pyrazolo[1,5-a]pyrimidine Derivatives as a Novel Series of Selective PI3Kδ Inhibitors: Part I-Indole Derivatives.
Stypik M, Zagozda M, Michałek S, Dymek B, Zdżalik-Bielecka D, Dziachan M, Orłowska N, Gunerka P, Turowski P, Hucz-Kalitowska J, Stańczak A, Stańczak P, Mulewski K, Smuga D, Stefaniak F, Gurba-Bryśkiewicz L, Leniak A, Ochal Z, Mach M, Dzwonek K, Lamparska-Przybysz M, Dubiel K, Wieczorek M. Stypik M, et al. Among authors: zagozda m. Pharmaceuticals (Basel). 2022 Jul 30;15(8):949. doi: 10.3390/ph15080949. Pharmaceuticals (Basel). 2022. PMID: 36015098 Free PMC article.
Development of the telescoped flow Pd-catalyzed aerobic alcohol oxidation/reductive amination sequence in the synthesis of new phosphatidylinositide 3-kinase inhibitor (CPL302415).
Michałek S, Maj AM, Gurba-Bryśkiewicz L, Maruszak W, Wiśniewski K, Zagozda M, Stypik M, Dubiel K, Wieczorek M. Michałek S, et al. Among authors: zagozda m. RSC Adv. 2024 Sep 6;14(39):28516-28523. doi: 10.1039/d4ra04923c. eCollection 2024 Sep 4. RSC Adv. 2024. PMID: 39247513 Free PMC article.
High levels of soluble vascular endothelial growth factor receptor 1/sFlt1 and low levels of vascular endothelial growth factor in follicular fluid on the day of oocyte retrieval correlate with ovarian hyperstimulation syndrom regardless of the stimulation protocol.
Jakimiuk AJ, Nowicka MA, Zagozda M, Koziol K, Lewandowski P, Issat T. Jakimiuk AJ, et al. Among authors: zagozda m. J Physiol Pharmacol. 2017 Jun;68(3):477-484. J Physiol Pharmacol. 2017. PMID: 28820403 Free article.
17 results