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140 results

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Page 1
Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans.
Kimbrel NA, Ashley-Koch AE, Qin XJ, Lindquist JH, Garrett ME, Dennis MF, Hair LP, Huffman JE, Jacobson DA, Madduri RK, Trafton JA, Coon H, Docherty AR, Mullins N, Ruderfer DM, Harvey PD, McMahon BH, Oslin DW, Beckham JC, Hauser ER, Hauser MA; Million Veteran Program Suicide Exemplar Workgroup, the International Suicide Genetics Consortium, the Veterans Affairs Mid-Atlantic Mental Illness Research, Education, and Clinical Center Workgroup, and the Veterans Affairs Million Veteran Program. Kimbrel NA, et al. Among authors: ruderfer dm. JAMA Psychiatry. 2023 Feb 1;80(2):135-145. doi: 10.1001/jamapsychiatry.2022.3896. JAMA Psychiatry. 2023. PMID: 36515925 Free PMC article.
Genome-wide association study identifies four pan-ancestry loci for suicidal ideation in the Million Veteran Program.
Ashley-Koch AE, Kimbrel NA, Qin XJ, Lindquist JH, Garrett ME, Dennis MF, Hair LP, Huffman JE, Jacobson DA, Madduri RK, Coon H, Docherty AR, Kang J, Mullins N, Ruderfer DM; VA Million Veteran Program (MVP); MVP Suicide Exemplar Workgroup; International Suicide Genetics Consortium; Harvey PD, McMahon BH, Oslin DW, Hauser ER, Hauser MA, Beckham JC. Ashley-Koch AE, et al. Among authors: ruderfer dm. PLoS Genet. 2023 Mar 20;19(3):e1010623. doi: 10.1371/journal.pgen.1010623. eCollection 2023 Mar. PLoS Genet. 2023. PMID: 36940203 Free PMC article.
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.
Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, Zang C, Ripke S, Bulik-Sullivan B, Stahl E; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium; Kähler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M, Pasaniuc B, Sullivan PF, Neale BM, Wray NR, Raychaudhuri S, Price AL; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium. Gusev A, et al. Am J Hum Genet. 2014 Nov 6;95(5):535-52. doi: 10.1016/j.ajhg.2014.10.004. Epub 2014 Nov 6. Am J Hum Genet. 2014. PMID: 25439723 Free PMC article.
Distinguishing different psychiatric disorders using DDx-PRS.
Peyrot WJ, Panagiotaropoulou G, Olde Loohuis LM, Adams MJ, Awasthi S, Ge T, McIntosh AM, Mitchell BL, Mullins N, O'Connell KS, Penninx BWJH, Posthuma D, Ripke S, Ruderfer DM, Uffelmann E, Vilhjalmsson BJ, Zhu Z; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Smoller JW, Price AL. Peyrot WJ, et al. Among authors: ruderfer dm. medRxiv [Preprint]. 2024 Feb 4:2024.02.02.24302228. doi: 10.1101/2024.02.02.24302228. medRxiv. 2024. PMID: 38352307 Free PMC article. Preprint.
Identifying modifiable comorbidities of schizophrenia by integrating electronic health records and polygenic risk.
Vessels T, Strayer N, Choi KW, Lee H, Zhang S, Han L, Morley TJ, Smoller JW, Xu Y, Ruderfer DM. Vessels T, et al. Among authors: ruderfer dm. medRxiv [Preprint]. 2023 Jun 5:2023.06.01.23290057. doi: 10.1101/2023.06.01.23290057. medRxiv. 2023. Update in: Biol Psychiatry Glob Open Sci. 2024 Feb 28;4(3):100297. doi: 10.1016/j.bpsgos.2024.100297 PMID: 37333378 Free PMC article. Updated. Preprint.
Analyses of GWAS signal using GRIN identify additional genes contributing to suicidal behavior.
Sullivan KA, Lane M, Cashman M, Miller JI, Pavicic M, Walker AM, Cliff A, Romero J, Qin X, Mullins N, Docherty A, Coon H, Ruderfer DM; International Suicide Genetics Consortium; VA Million Veteran Program; MVP Suicide Exemplar Workgroup; Garvin MR, Pestian JP, Ashley-Koch AE, Beckham JC, McMahon B, Oslin DW, Kimbrel NA, Jacobson DA, Kainer D. Sullivan KA, et al. Among authors: ruderfer dm. Commun Biol. 2024 Oct 21;7(1):1360. doi: 10.1038/s42003-024-06943-7. Commun Biol. 2024. PMID: 39433874 Free PMC article.
PheMIME: an interactive web app and knowledge base for phenome-wide, multi-institutional multimorbidity analysis.
Zhang S, Strayer N, Vessels T, Choi K, Wang GW, Li Y, Bejan CA, Hsi RS, Bick AG, Velez Edwards DR, Savona MR, Phillips EJ, Pulley JM, Self WH, Hopkins WC, Roden DM, Smoller JW, Ruderfer DM, Xu Y. Zhang S, et al. Among authors: ruderfer dm. J Am Med Inform Assoc. 2024 Nov 1;31(11):2440-2446. doi: 10.1093/jamia/ocae182. J Am Med Inform Assoc. 2024. PMID: 39127052 Free PMC article.
Sleep patterns and risk of chronic disease as measured by long-term monitoring with commercial wearable devices in the All of Us Research Program.
Zheng NS, Annis J, Master H, Han L, Gleichauf K, Ching JH, Nasser M, Coleman P, Desine S, Ruderfer DM, Hernandez J, Schneider LD, Brittain EL. Zheng NS, et al. Among authors: ruderfer dm. Nat Med. 2024 Sep;30(9):2648-2656. doi: 10.1038/s41591-024-03155-8. Epub 2024 Jul 19. Nat Med. 2024. PMID: 39030265 Free PMC article.
140 results