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Caspase-1 and the inflammasome promote polycystic kidney disease progression.
Swenson-Fields KI, Ward CJ, Lopez ME, Fross S, Heimes Dillon AL, Meisenheimer JD, Rabbani AJ, Wedlock E, Basu MK, Jansson KP, Rowe PS, Stubbs JR, Wallace DP, Vitek MP, Fields TA. Swenson-Fields KI, et al. Among authors: wallace dp. Front Mol Biosci. 2022 Nov 29;9:971219. doi: 10.3389/fmolb.2022.971219. eCollection 2022. Front Mol Biosci. 2022. PMID: 36523654 Free PMC article.
Detected renal cysts are tips of the iceberg in adults with ADPKD.
Grantham JJ, Mulamalla S, Grantham CJ, Wallace DP, Cook LT, Wetzel LH, Fields TA, Bae KT. Grantham JJ, et al. Among authors: wallace dp. Clin J Am Soc Nephrol. 2012 Jul;7(7):1087-93. doi: 10.2215/CJN.00900112. Epub 2012 May 10. Clin J Am Soc Nephrol. 2012. PMID: 22580785 Free PMC article.
Endogenous concentrations of ouabain act as a cofactor to stimulate fluid secretion and cyst growth of in vitro ADPKD models via cAMP and EGFR-Src-MEK pathways.
Jansson K, Nguyen AN, Magenheimer BS, Reif GA, Aramadhaka LR, Bello-Reuss E, Wallace DP, Calvet JP, Blanco G. Jansson K, et al. Among authors: wallace dp. Am J Physiol Renal Physiol. 2012 Oct;303(7):F982-90. doi: 10.1152/ajprenal.00677.2011. Epub 2012 Aug 1. Am J Physiol Renal Physiol. 2012. PMID: 22859406 Free PMC article.
Macrophages promote polycystic kidney disease progression.
Swenson-Fields KI, Vivian CJ, Salah SM, Peda JD, Davis BM, van Rooijen N, Wallace DP, Fields TA. Swenson-Fields KI, et al. Among authors: wallace dp. Kidney Int. 2013 May;83(5):855-64. doi: 10.1038/ki.2012.446. Epub 2013 Feb 20. Kidney Int. 2013. PMID: 23423256 Free PMC article.
137 results