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Page 1
Predicting AT(N) pathologies in Alzheimer's disease from blood-based proteomic data using neural networks.
Zhang Y, Ghose U, Buckley NJ, Engelborghs S, Sleegers K, Frisoni GB, Wallin A, Lleó A, Popp J, Martinez-Lage P, Legido-Quigley C, Barkhof F, Zetterberg H, Visser PJ, Bertram L, Lovestone S, Nevado-Holgado AJ, Shi L. Zhang Y, et al. Front Aging Neurosci. 2022 Nov 29;14:1040001. doi: 10.3389/fnagi.2022.1040001. eCollection 2022. Front Aging Neurosci. 2022. PMID: 36523958 Free PMC article.
Rifaximin-α for liver fibrosis in patients with alcohol-related liver disease (GALA-RIF): a randomised, double-blind, placebo-controlled, phase 2 trial.
Israelsen M, Madsen BS, Torp N, Johansen S, Hansen CD, Detlefsen S, Andersen P, Hansen JK, Lindvig KP, Rasmussen DN, Thorhauge KH, Kjærgaard M, Karsdal M, Hansen T, Arumugam M, Trebicka J, Thiele M, Krag A; GALAXY; MicrobLiver Consortia. Israelsen M, et al. Lancet Gastroenterol Hepatol. 2023 Jun;8(6):523-532. doi: 10.1016/S2468-1253(23)00010-9. Epub 2023 Mar 6. Lancet Gastroenterol Hepatol. 2023. PMID: 36893774 Free PMC article. Clinical Trial.
Clinical care advice for monitoring of islet autoantibody positive individuals with presymptomatic type 1 diabetes.
Hendriks AEJ, Marcovecchio ML, Besser REJ, Bonifacio E, Casteels K, Elding Larsson H, Gemulla G, Lundgren M, Kordonouri O, Mallone R, Pociot F, Szypowska A, Toppari J, Berge TVD, Ziegler AG, Mathieu C, Achenbach P; INNODIA consortium, the Fr1da Study Group and the GPPAD Study Group. Hendriks AEJ, et al. Diabetes Metab Res Rev. 2024 Feb;40(2):e3777. doi: 10.1002/dmrr.3777. Diabetes Metab Res Rev. 2024. PMID: 38375753
Rare variants in IFFO1, DTNB, NLRC3 and SLC22A10 associate with Alzheimer's disease CSF profile of neuronal injury and inflammation.
Neumann A, Küçükali F, Bos I, Vos SJB, Engelborghs S, De Pooter T, Joris G, De Rijk P, De Roeck E, Tsolaki M, Verhey F, Martinez-Lage P, Tainta M, Frisoni G, Blin O, Richardson J, Bordet R, Scheltens P, Popp J, Peyratout G, Johannsen P, Frölich L, Vandenberghe R, Freund-Levi Y, Streffer J, Lovestone S, Legido-Quigley C, Ten Kate M, Barkhof F, Strazisar M, Zetterberg H, Bertram L, Visser PJ, van Broeckhoven C, Sleegers K; EMIF-AD study group. Neumann A, et al. Mol Psychiatry. 2022 Apr;27(4):1990-1999. doi: 10.1038/s41380-022-01437-6. Epub 2022 Feb 16. Mol Psychiatry. 2022. PMID: 35173266 Free PMC article.
Whole-exome rare-variant analysis of Alzheimer's disease and related biomarker traits.
Küçükali F, Neumann A, Van Dongen J, De Pooter T, Joris G, De Rijk P, Ohlei O, Dobricic V, Bos I, Vos SJB, Engelborghs S, De Roeck E, Vandenberghe R, Gabel S, Meersmans K, Tsolaki M, Verhey F, Martinez-Lage P, Tainta M, Frisoni G, Blin O, Richardson JC, Bordet R; Alzheimer's Disease Neuroimaging Initiative (ADNI); Scheltens P, Popp J, Peyratout G, Johannsen P, Frölich L, Freund-Levi Y, Streffer J, Lovestone S, Legido-Quigley C, Kate MT, Barkhof F, Zetterberg H, Bertram L, Strazisar M, Visser PJ, Van Broeckhoven C, Sleegers K; EMIF-AD Study Group. Küçükali F, et al. Alzheimers Dement. 2023 Jun;19(6):2317-2331. doi: 10.1002/alz.12842. Epub 2022 Dec 4. Alzheimers Dement. 2023. PMID: 36464806 Free article.
Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN-derived networks and highlights causal links in Alzheimer's disease.
Shi L, Xu J, Green R, Wretlind A, Homann J, Buckley NJ, Tijms BM, Vos SJB, Lill CM, Kate MT, Engelborghs S, Sleegers K, Frisoni GB, Wallin A, Lleó A, Popp J, Martinez-Lage P, Streffer J, Barkhof F, Zetterberg H, Visser PJ, Lovestone S, Bertram L, Nevado-Holgado AJ, Proitsi P, Legido-Quigley C. Shi L, et al. Alzheimers Dement. 2023 Aug;19(8):3350-3364. doi: 10.1002/alz.12961. Epub 2023 Feb 15. Alzheimers Dement. 2023. PMID: 36790009
Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning.
Neumann A, Ohlei O, Küçükali F, Bos IJ, Timsina J, Vos S, Prokopenko D, Tijms BM, Andreasson U, Blennow K, Vandenberghe R, Scheltens P, Teunissen CE, Engelborghs S, Frisoni GB, Blin O, Richardson JC, Bordet R, Lleó A, Alcolea D, Popp J, Marsh TW, Gorijala P, Clark C, Peyratout G, Martinez-Lage P, Tainta M, Dobson RJB, Legido-Quigley C, Van Broeckhoven C, Tanzi RE, Ten Kate M, Lill CM, Barkhof F, Cruchaga C, Lovestone S, Streffer J, Zetterberg H, Visser PJ, Sleegers K, Bertram L; EMIF-AD & ADNI study group. Neumann A, et al. Genome Med. 2023 Oct 4;15(1):79. doi: 10.1186/s13073-023-01233-z. Genome Med. 2023. PMID: 37794492 Free PMC article.
Paired plasma lipidomics and proteomics analysis in the conversion from mild cognitive impairment to Alzheimer's disease.
Gómez-Pascual A, Naccache T, Xu J, Hooshmand K, Wretlind A, Gabrielli M, Lombardo MT, Shi L, Buckley NJ, Tijms BM, Vos SJB, Ten Kate M, Engelborghs S, Sleegers K, Frisoni GB, Wallin A, Lleó A, Popp J, Martinez-Lage P, Streffer J, Barkhof F, Zetterberg H, Visser PJ, Lovestone S, Bertram L, Nevado-Holgado AJ, Gualerzi A, Picciolini S, Proitsi P, Verderio C, Botía JA, Legido-Quigley C. Gómez-Pascual A, et al. Among authors: legido quigley c. Comput Biol Med. 2024 Jun;176:108588. doi: 10.1016/j.compbiomed.2024.108588. Epub 2024 May 13. Comput Biol Med. 2024. PMID: 38761503 Free article.
Disentangling Independent and Mediated Causal Relationships Between Blood Metabolites, Cognitive Factors, and Alzheimer's Disease.
Lord J, Green R, Choi SW, Hübel C, Aarsland D, Velayudhan L, Sham P, Legido-Quigley C, Richards M, Dobson R, Proitsi P; Alzheimer’s Disease Neuroimaging Initiative; GERAD1 Consortium, and AddNeuroMed. Lord J, et al. Biol Psychiatry Glob Open Sci. 2021 Aug 4;2(2):167-179. doi: 10.1016/j.bpsgos.2021.07.010. eCollection 2022 Apr. Biol Psychiatry Glob Open Sci. 2021. PMID: 36325159 Free PMC article.
153 results