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mRNA vaccines against SARS-CoV-2 induce comparably low long-term IgG Fc galactosylation and sialylation levels but increasing long-term IgG4 responses compared to an adenovirus-based vaccine.
Buhre JS, Pongracz T, Künsting I, Lixenfeld AS, Wang W, Nouta J, Lehrian S, Schmelter F, Lunding HB, Dühring L, Kern C, Petry J, Martin EL, Föh B, Steinhaus M, von Kopylow V, Sina C, Graf T, Rahmöller J, Wuhrer M, Ehlers M. Buhre JS, et al. Among authors: lixenfeld as. Front Immunol. 2023 Jan 12;13:1020844. doi: 10.3389/fimmu.2022.1020844. eCollection 2022. Front Immunol. 2023. PMID: 36713457 Free PMC article.
The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees.
Van Coillie J, Pongracz T, Rahmöller J, Chen HJ, Geyer CE, van Vught LA, Buhre JS, Šuštić T, van Osch TLJ, Steenhuis M, Hoepel W, Wang W, Lixenfeld AS, Nouta J, Keijzer S, Linty F, Visser R, Larsen MD, Martin EL, Künsting I, Lehrian S, von Kopylow V, Kern C, Lunding HB, de Winther M, van Mourik N, Rispens T, Graf T, Slim MA, Minnaar RP, Bomers MK, Sikkens JJ, Vlaar APJ, van der Schoot CE, den Dunnen J, Wuhrer M, Ehlers M, Vidarsson G; Fatebenefratelli-Sacco Infectious Diseases Physicians group; UMC COVID-19 S3/HCW study group. Van Coillie J, et al. Among authors: lixenfeld as. EBioMedicine. 2023 Jan;87:104408. doi: 10.1016/j.ebiom.2022.104408. Epub 2022 Dec 16. EBioMedicine. 2023. PMID: 36529104 Free PMC article.
Metabolic and Lipidomic Markers Differentiate COVID-19 From Non-Hospitalized and Other Intensive Care Patients.
Schmelter F, Föh B, Mallagaray A, Rahmöller J, Ehlers M, Lehrian S, von Kopylow V, Künsting I, Lixenfeld AS, Martin E, Ragab M, Meyer-Saraei R, Kreutzmann F, Eitel I, Taube S, Käding N, Jantzen E, Graf T, Sina C, Günther UL. Schmelter F, et al. Among authors: lixenfeld as. Front Mol Biosci. 2021 Dec 2;8:737039. doi: 10.3389/fmolb.2021.737039. eCollection 2021. Front Mol Biosci. 2021. PMID: 34938772 Free PMC article.