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A molecular signature defining exercise adaptation with ageing and in vivo partial reprogramming in skeletal muscle.
Jones RG 3rd, Dimet-Wiley A, Haghani A, da Silva FM, Brightwell CR, Lim S, Khadgi S, Wen Y, Dungan CM, Brooke RT, Greene NP, Peterson CA, McCarthy JJ, Horvath S, Watowich SJ, Fry CS, Murach KA. Jones RG 3rd, et al. Among authors: brightwell cr. J Physiol. 2023 Feb;601(4):763-782. doi: 10.1113/JP283836. Epub 2023 Jan 24. J Physiol. 2023. PMID: 36533424 Free PMC article.
Skeletal muscle fibrosis is associated with decreased muscle inflammation and weakness in patients with chronic kidney disease.
Abramowitz MK, Paredes W, Zhang K, Brightwell CR, Newsom JN, Kwon HJ, Custodio M, Buttar RS, Farooq H, Zaidi B, Pai R, Pessin JE, Hawkins M, Fry CS. Abramowitz MK, et al. Among authors: brightwell cr. Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1658-F1669. doi: 10.1152/ajprenal.00314.2018. Epub 2018 Oct 3. Am J Physiol Renal Physiol. 2018. PMID: 30280599 Free PMC article.
Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle.
Neelakantan H, Brightwell CR, Graber TG, Maroto R, Wang HL, McHardy SF, Papaconstantinou J, Fry CS, Watowich SJ. Neelakantan H, et al. Among authors: brightwell cr. Biochem Pharmacol. 2019 May;163:481-492. doi: 10.1016/j.bcp.2019.02.008. Epub 2019 Feb 10. Biochem Pharmacol. 2019. PMID: 30753815 Free PMC article.
34 results