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Stromal Reprogramming through Dual PDGFRα/β Blockade Boosts the Efficacy of Anti-PD-1 Immunotherapy in Fibrotic Tumors.
Akiyama T, Yasuda T, Uchihara T, Yasuda-Yoshihara N, Tan BJY, Yonemura A, Semba T, Yamasaki J, Komohara Y, Ohnishi K, Wei F, Fu L, Zhang J, Kitamura F, Yamashita K, Eto K, Iwagami S, Tsukamoto H, Umemoto T, Masuda M, Nagano O, Satou Y, Saya H, Tan P, Baba H, Ishimoto T. Akiyama T, et al. Among authors: fu l. Cancer Res. 2023 Mar 2;83(5):753-770. doi: 10.1158/0008-5472.CAN-22-1890. Cancer Res. 2023. PMID: 36543251
Impact of loss-of-function mutations at the RNF43 locus on colorectal cancer development and progression.
Eto T, Miyake K, Nosho K, Ohmuraya M, Imamura Y, Arima K, Kanno S, Fu L, Kiyozumi Y, Izumi D, Sugihara H, Hiyoshi Y, Miyamoto Y, Sawayama H, Iwatsuki M, Baba Y, Yoshida N, Furukawa T, Araki K, Baba H, Ishimoto T. Eto T, et al. Among authors: fu l. J Pathol. 2018 Aug;245(4):445-455. doi: 10.1002/path.5098. Epub 2018 Jun 20. J Pathol. 2018. PMID: 29756208
Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination.
Yasuda T, Koiwa M, Yonemura A, Miyake K, Kariya R, Kubota S, Yokomizo-Nakano T, Yasuda-Yoshihara N, Uchihara T, Itoyama R, Bu L, Fu L, Arima K, Izumi D, Iwagami S, Eto K, Iwatsuki M, Baba Y, Yoshida N, Ohguchi H, Okada S, Matsusaki K, Sashida G, Takahashi A, Tan P, Baba H, Ishimoto T. Yasuda T, et al. Among authors: fu l. Cell Rep. 2021 Feb 23;34(8):108779. doi: 10.1016/j.celrep.2021.108779. Cell Rep. 2021. PMID: 33626356 Free article.
The Gut Microbiota in Inflammatory Bowel Disease.
Qiu P, Ishimoto T, Fu L, Zhang J, Zhang Z, Liu Y. Qiu P, et al. Among authors: fu l. Front Cell Infect Microbiol. 2022 Feb 22;12:733992. doi: 10.3389/fcimb.2022.733992. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35273921 Free PMC article. Review.
Tumor microenvironmental 15-PGDH depletion promotes fibrotic tumor formation and angiogenesis in pancreatic cancer.
Bu L, Yonemura A, Yasuda-Yoshihara N, Uchihara T, Ismagulov G, Takasugi S, Yasuda T, Okamoto Y, Kitamura F, Akiyama T, Arima K, Itoyama R, Zhang J, Fu L, Hu X, Wei F, Arima Y, Moroishi T, Nishiyama K, Sheng G, Mukunoki T, Otani J, Baba H, Ishimoto T. Bu L, et al. Among authors: fu l. Cancer Sci. 2022 Oct;113(10):3579-3592. doi: 10.1111/cas.15495. Epub 2022 Aug 23. Cancer Sci. 2022. PMID: 35848891 Free PMC article.
IL-1β derived from mixed-polarized macrophages activates fibroblasts and synergistically forms a cancer-promoting microenvironment.
Zhang J, Fu L, Yasuda-Yoshihara N, Yonemura A, Wei F, Bu L, Hu X, Akiyama T, Kitamura F, Yasuda T, Semba T, Uchihara T, Itoyama R, Yamashita K, Eto K, Iwagami S, Yashiro M, Komohara Y, Baba H, Ishimoto T. Zhang J, et al. Among authors: fu l. Gastric Cancer. 2023 Mar;26(2):187-202. doi: 10.1007/s10120-022-01352-3. Epub 2022 Dec 13. Gastric Cancer. 2023. PMID: 36513910
A novel tdTomato transgenic mouse model to visualize FAP-positive cancer-associated fibroblasts.
Wei F, Uchihara T, Yonemura A, Yasuda-Yoshihara N, Yasuda T, Semba T, Fukuda M, Akiyama T, Kitamura F, Bu L, Hu X, Fu L, Zhang J, Kariya R, Yamasaki J, Aihara K, Yamashita K, Nagano O, Okada S, Baba H, Ishimoto T. Wei F, et al. Among authors: fu l. FEBS J. 2023 May;290(10):2604-2615. doi: 10.1111/febs.16712. Epub 2023 Jan 3. FEBS J. 2023. PMID: 36565059 Free article.
8,651 results