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Stromal Reprogramming through Dual PDGFRα/β Blockade Boosts the Efficacy of Anti-PD-1 Immunotherapy in Fibrotic Tumors.
Akiyama T, Yasuda T, Uchihara T, Yasuda-Yoshihara N, Tan BJY, Yonemura A, Semba T, Yamasaki J, Komohara Y, Ohnishi K, Wei F, Fu L, Zhang J, Kitamura F, Yamashita K, Eto K, Iwagami S, Tsukamoto H, Umemoto T, Masuda M, Nagano O, Satou Y, Saya H, Tan P, Baba H, Ishimoto T. Akiyama T, et al. Among authors: kitamura f. Cancer Res. 2023 Mar 2;83(5):753-770. doi: 10.1158/0008-5472.CAN-22-1890. Cancer Res. 2023. PMID: 36543251
Intraoperative bile culture helps choosing antibiotics in pancreaticoduodenectomy: Mechanistic profiling study of complex rink between bacterobilia and postoperative complications.
Itoyama R, Okabe H, Yamashita YI, Kitamura F, Uemura N, Nakao Y, Yusa T, Imai K, Hayashi H, Baba H. Itoyama R, et al. Among authors: kitamura f. J Hepatobiliary Pancreat Sci. 2021 Dec;28(12):1107-1114. doi: 10.1002/jhbp.887. Epub 2021 Feb 11. J Hepatobiliary Pancreat Sci. 2021. PMID: 33453135
Metabolic shift to serine biosynthesis through 3-PG accumulation and PHGDH induction promotes tumor growth in pancreatic cancer.
Itoyama R, Yasuda-Yoshihara N, Kitamura F, Yasuda T, Bu L, Yonemura A, Uchihara T, Arima K, Hu X, Jun Z, Okamoto Y, Akiyama T, Yamashita K, Nakao Y, Yusa T, Kitano Y, Higashi T, Miyata T, Imai K, Hayashi H, Yamashita YI, Mikawa T, Kondoh H, Baba H, Ishimoto T. Itoyama R, et al. Among authors: kitamura f. Cancer Lett. 2021 Dec 28;523:29-42. doi: 10.1016/j.canlet.2021.09.007. Epub 2021 Sep 9. Cancer Lett. 2021. PMID: 34508795
Intracellular MUC20 variant 2 maintains mitochondrial calcium homeostasis and enhances drug resistance in gastric cancer.
Fu L, Yonemura A, Yasuda-Yoshihara N, Umemoto T, Zhang J, Yasuda T, Uchihara T, Akiyama T, Kitamura F, Yamashita K, Okamoto Y, Bu L, Wei F, Hu X, Liu Y, Ajani JA, Tan P, Baba H, Ishimoto T. Fu L, et al. Among authors: kitamura f. Gastric Cancer. 2022 May;25(3):542-557. doi: 10.1007/s10120-022-01283-z. Epub 2022 Feb 15. Gastric Cancer. 2022. PMID: 35166958
Tumor microenvironmental 15-PGDH depletion promotes fibrotic tumor formation and angiogenesis in pancreatic cancer.
Bu L, Yonemura A, Yasuda-Yoshihara N, Uchihara T, Ismagulov G, Takasugi S, Yasuda T, Okamoto Y, Kitamura F, Akiyama T, Arima K, Itoyama R, Zhang J, Fu L, Hu X, Wei F, Arima Y, Moroishi T, Nishiyama K, Sheng G, Mukunoki T, Otani J, Baba H, Ishimoto T. Bu L, et al. Among authors: kitamura f. Cancer Sci. 2022 Oct;113(10):3579-3592. doi: 10.1111/cas.15495. Epub 2022 Aug 23. Cancer Sci. 2022. PMID: 35848891 Free PMC article.
Thrombospondin-1 overexpression stimulates loss of Smad4 and accelerates malignant behavior via TGF-β signal activation in pancreatic ductal adenocarcinoma.
Matsumura K, Hayashi H, Uemura N, Ogata Y, Zhao L, Sato H, Shiraishi Y, Kuroki H, Kitamura F, Kaida T, Higashi T, Nakagawa S, Mima K, Imai K, Yamashita YI, Baba H. Matsumura K, et al. Among authors: kitamura f. Transl Oncol. 2022 Dec;26:101533. doi: 10.1016/j.tranon.2022.101533. Epub 2022 Sep 15. Transl Oncol. 2022. PMID: 36115074 Free PMC article.
IL-1β derived from mixed-polarized macrophages activates fibroblasts and synergistically forms a cancer-promoting microenvironment.
Zhang J, Fu L, Yasuda-Yoshihara N, Yonemura A, Wei F, Bu L, Hu X, Akiyama T, Kitamura F, Yasuda T, Semba T, Uchihara T, Itoyama R, Yamashita K, Eto K, Iwagami S, Yashiro M, Komohara Y, Baba H, Ishimoto T. Zhang J, et al. Among authors: kitamura f. Gastric Cancer. 2023 Mar;26(2):187-202. doi: 10.1007/s10120-022-01352-3. Epub 2022 Dec 13. Gastric Cancer. 2023. PMID: 36513910
213 results