Inada T - Search Results

1

The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3.

Ishimura R, El-Gowily AH, Noshiro D, Komatsu-Hirota S, Ono Y, Shindo M, Hatta T, Abe M, Uemura T, Lee-Okada HC, Mohamed TM, Yokomizo T, Ueno T, Sakimura K, Natsume T, Sorimachi H, Inada T, Waguri S, Noda NN, Komatsu M. Ishimura R, et al. Among authors: inada t. Nat Commun. 2022 Dec 21;13(1):7857. doi: 10.1038/s41467-022-35501-0. Nat Commun. 2022. PMID: 36543799 Free PMC article.

2

Ubiquitination of stalled ribosome triggers ribosome-associated quality control.

Matsuo Y, Ikeuchi K, Saeki Y, Iwasaki S, Schmidt C, Udagawa T, Sato F, Tsuchiya H, Becker T, Tanaka K, Ingolia NT, Beckmann R, Inada T. Matsuo Y, et al. Among authors: inada t. Nat Commun. 2017 Jul 31;8(1):159. doi: 10.1038/s41467-017-00188-1. Nat Commun. 2017. PMID: 28757607 Free PMC article.

3

TRIM48 Promotes ASK1 Activation and Cell Death through Ubiquitination-Dependent Degradation of the ASK1-Negative Regulator PRMT1.

Hirata Y, Katagiri K, Nagaoka K, Morishita T, Kudoh Y, Hatta T, Naguro I, Kano K, Udagawa T, Natsume T, Aoki J, Inada T, Noguchi T, Ichijo H, Matsuzawa A. Hirata Y, et al. Among authors: inada t. Cell Rep. 2017 Nov 28;21(9):2447-2457. doi: 10.1016/j.celrep.2017.11.007. Cell Rep. 2017. PMID: 29186683 Free article.

4

RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1.

Matsuo Y, Tesina P, Nakajima S, Mizuno M, Endo A, Buschauer R, Cheng J, Shounai O, Ikeuchi K, Saeki Y, Becker T, Beckmann R, Inada T. Matsuo Y, et al. Among authors: inada t. Nat Struct Mol Biol. 2020 Apr;27(4):323-332. doi: 10.1038/s41594-020-0393-9. Epub 2020 Mar 23. Nat Struct Mol Biol. 2020. PMID: 32203490

5

Failure to Degrade CAT-Tailed Proteins Disrupts Neuronal Morphogenesis and Cell Survival.

Udagawa T, Seki M, Okuyama T, Adachi S, Natsume T, Noguchi T, Matsuzawa A, Inada T. Udagawa T, et al. Among authors: inada t. Cell Rep. 2021 Jan 5;34(1):108599. doi: 10.1016/j.celrep.2020.108599. Cell Rep. 2021. PMID: 33406423 Free article.

6

Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover.

Li S, Ikeuchi K, Kato M, Buschauer R, Sugiyama T, Adachi S, Kusano H, Natsume T, Berninghausen O, Matsuo Y, Becker T, Beckmann R, Inada T. Li S, et al. Among authors: inada t. Mol Cell. 2022 Sep 15;82(18):3424-3437.e8. doi: 10.1016/j.molcel.2022.08.018. Mol Cell. 2022. PMID: 36113412 Free article.

7

A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.

Narita M, Denk T, Matsuo Y, Sugiyama T, Kikuguchi C, Ito S, Sato N, Suzuki T, Hashimoto S, Machová I, Tesina P, Beckmann R, Inada T. Narita M, et al. Among authors: inada t. Nat Commun. 2022 Oct 27;13(1):6411. doi: 10.1038/s41467-022-34097-9. Nat Commun. 2022. PMID: 36302773 Free PMC article.

8

Decoding of the ubiquitin code for clearance of colliding ribosomes by the RQT complex.

Matsuo Y, Uchihashi T, Inada T. Matsuo Y, et al. Among authors: inada t. Nat Commun. 2023 Jan 10;14(1):79. doi: 10.1038/s41467-022-35608-4. Nat Commun. 2023. PMID: 36627279 Free PMC article.

9

Structural basis for clearing of ribosome collisions by the RQT complex.

Best K, Ikeuchi K, Kater L, Best D, Musial J, Matsuo Y, Berninghausen O, Becker T, Inada T, Beckmann R. Best K, et al. Among authors: inada t. Nat Commun. 2023 Feb 17;14(1):921. doi: 10.1038/s41467-023-36230-8. Nat Commun. 2023. PMID: 36801861 Free PMC article.

10

Mechanistic insights into the roles of the UFM1 E3 ligase complex in ufmylation and ribosome-associated protein quality control.

Ishimura R, Ito S, Mao G, Komatsu-Hirota S, Inada T, Noda NN, Komatsu M. Ishimura R, et al. Among authors: inada t. Sci Adv. 2023 Aug 18;9(33):eadh3635. doi: 10.1126/sciadv.adh3635. Epub 2023 Aug 18. Sci Adv. 2023. PMID: 37595036 Free PMC article.

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