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The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3.
Ishimura R, El-Gowily AH, Noshiro D, Komatsu-Hirota S, Ono Y, Shindo M, Hatta T, Abe M, Uemura T, Lee-Okada HC, Mohamed TM, Yokomizo T, Ueno T, Sakimura K, Natsume T, Sorimachi H, Inada T, Waguri S, Noda NN, Komatsu M. Ishimura R, et al. Among authors: uemura t. Nat Commun. 2022 Dec 21;13(1):7857. doi: 10.1038/s41467-022-35501-0. Nat Commun. 2022. PMID: 36543799 Free PMC article.
Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway.
Kageyama S, Sou YS, Uemura T, Kametaka S, Saito T, Ishimura R, Kouno T, Bedford L, Mayer RJ, Lee MS, Yamamoto M, Waguri S, Tanaka K, Komatsu M. Kageyama S, et al. Among authors: uemura t. J Biol Chem. 2014 Sep 5;289(36):24944-55. doi: 10.1074/jbc.M114.580357. Epub 2014 Jul 21. J Biol Chem. 2014. PMID: 25049227 Free PMC article.
Activation of STING requires palmitoylation at the Golgi.
Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, Barber GN, Arai H, Taguchi T. Mukai K, et al. Among authors: uemura t. Nat Commun. 2016 Jun 21;7:11932. doi: 10.1038/ncomms11932. Nat Commun. 2016. PMID: 27324217 Free PMC article.
p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming.
Saito T, Ichimura Y, Taguchi K, Suzuki T, Mizushima T, Takagi K, Hirose Y, Nagahashi M, Iso T, Fukutomi T, Ohishi M, Endo K, Uemura T, Nishito Y, Okuda S, Obata M, Kouno T, Imamura R, Tada Y, Obata R, Yasuda D, Takahashi K, Fujimura T, Pi J, Lee MS, Ueno T, Ohe T, Mashino T, Wakai T, Kojima H, Okabe T, Nagano T, Motohashi H, Waguri S, Soga T, Yamamoto M, Tanaka K, Komatsu M. Saito T, et al. Among authors: uemura t. Nat Commun. 2016 Jun 27;7:12030. doi: 10.1038/ncomms12030. Nat Commun. 2016. PMID: 27345495 Free PMC article.
1,489 results