Shaw LM - Search Results

1

The Insulin-like Growth Factor Signaling Pathway in Breast Cancer: An Elusive Therapeutic Target.

Lee JS, Tocheny CE, Shaw LM. Lee JS, et al. Among authors: shaw lm. Life (Basel). 2022 Nov 29;12(12):1992. doi: 10.3390/life12121992. Life (Basel). 2022. PMID: 36556357 Free PMC article. Review.

2

Diversity of insulin and IGF signaling in breast cancer: Implications for therapy.

Lero MW, Shaw LM. Lero MW, et al. Among authors: shaw lm. Mol Cell Endocrinol. 2021 May 1;527:111213. doi: 10.1016/j.mce.2021.111213. Epub 2021 Feb 17. Mol Cell Endocrinol. 2021. PMID: 33607269 Free PMC article. Review.

3

The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC.

Lee JS, Lero MW, Mercado-Matos J, Zhu S, Jo M, Tocheny CE, Morgan JS, Shaw LM. Lee JS, et al. Among authors: shaw lm. Cell Rep. 2022 Dec 6;41(10):111759. doi: 10.1016/j.celrep.2022.111759. Cell Rep. 2022. PMID: 36476848 Free PMC article.

4

Fluorescent tagging of endogenous IRS2 with an auxin-dependent degron to assess dynamic intracellular localization and function.

Jo M, Lee JS, Tocheny CE, Lero MW, Bui QT, Morgan JS, Shaw LM. Jo M, et al. Among authors: shaw lm. J Biol Chem. 2024 Sep 19;300(11):107796. doi: 10.1016/j.jbc.2024.107796. Online ahead of print. J Biol Chem. 2024. PMID: 39305958 Free PMC article.

5

Divergent roles for IRS-1 and IRS-2 in breast cancer metastasis.

Gibson SL, Ma Z, Shaw LM. Gibson SL, et al. Among authors: shaw lm. Cell Cycle. 2007 Mar 15;6(6):631-7. doi: 10.4161/cc.6.6.3987. Epub 2007 Mar 7. Cell Cycle. 2007. PMID: 17361103 Review.

6

Expression and function of the insulin receptor substrate proteins in cancer.

Mardilovich K, Pankratz SL, Shaw LM. Mardilovich K, et al. Among authors: shaw lm. Cell Commun Signal. 2009 Jun 17;7:14. doi: 10.1186/1478-811X-7-14. Cell Commun Signal. 2009. PMID: 19534786 Free PMC article.

7

Hypoxia regulates insulin receptor substrate-2 expression to promote breast carcinoma cell survival and invasion.

Mardilovich K, Shaw LM. Mardilovich K, et al. Among authors: shaw lm. Cancer Res. 2009 Dec 1;69(23):8894-901. doi: 10.1158/0008-5472.CAN-09-1152. Epub 2009 Nov 17. Cancer Res. 2009. PMID: 19920186 Free PMC article.

8

Membrane localization of insulin receptor substrate-2 (IRS-2) is associated with decreased overall survival in breast cancer.

Clark JL, Dresser K, Hsieh CC, Sabel M, Kleer CG, Khan A, Shaw LM. Clark JL, et al. Among authors: shaw lm. Breast Cancer Res Treat. 2011 Dec;130(3):759-72. doi: 10.1007/s10549-011-1353-1. Epub 2011 Jan 22. Breast Cancer Res Treat. 2011. PMID: 21258861 Free PMC article.

9

Beclin 1 regulates growth factor receptor signaling in breast cancer.

Rohatgi RA, Janusis J, Leonard D, Bellvé KD, Fogarty KE, Baehrecke EH, Corvera S, Shaw LM. Rohatgi RA, et al. Among authors: shaw lm. Oncogene. 2015 Oct 16;34(42):5352-62. doi: 10.1038/onc.2014.454. Epub 2015 Feb 2. Oncogene. 2015. PMID: 25639875 Free PMC article.

10

Differential involvement of the microtubule cytoskeleton in insulin receptor substrate 1 (IRS-1) and IRS-2 signaling to AKT determines the response to microtubule disruption in breast carcinoma cells.

Mercado-Matos J, Clark JL, Piper AJ, Janusis J, Shaw LM. Mercado-Matos J, et al. Among authors: shaw lm. J Biol Chem. 2017 May 12;292(19):7806-7816. doi: 10.1074/jbc.M117.785832. Epub 2017 Mar 20. J Biol Chem. 2017. PMID: 28320862 Free PMC article.

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