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Correction: SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing.
Redin E, Sridhar H, Zhan YA, Pereira Mello B, Zhong H, Durani V, Sabet A, Manoj P, Linkov I, Qiu J, Koche RP, de Stanchina E, Astorkia M, Betel D, Quintanal-Villalonga Á, Rudin CM. Redin E, et al. Among authors: manoj p. J Hematol Oncol. 2024 Sep 29;17(1):89. doi: 10.1186/s13045-024-01609-7. J Hematol Oncol. 2024. PMID: 39343962 Free PMC article. No abstract available.
ATR inhibition activates cancer cell cGAS/STING-interferon signaling and promotes antitumor immunity in small-cell lung cancer.
Taniguchi H, Chakraborty S, Takahashi N, Banerjee A, Caeser R, Zhan YA, Tischfield SE, Chow A, Nguyen EM, Villalonga ÁQ, Manoj P, Shah NS, Rosario S, Hayatt O, Qu R, de Stanchina E, Chan J, Mukae H, Thomas A, Rudin CM, Sen T. Taniguchi H, et al. Among authors: manoj p. Sci Adv. 2024 Sep 27;10(39):eado4618. doi: 10.1126/sciadv.ado4618. Epub 2024 Sep 27. Sci Adv. 2024. PMID: 39331709 Free PMC article.
Chromothripsis-mediated small cell lung carcinoma.
Rekhtman N, Tischfield SE, Febres-Aldana CA, Lee JJ, Chang JC, Herzberg BO, Selenica P, Woo HJ, Vanderbilt CM, Yang SR, Xu F, Bowman AS, da Silva EM, Noronha AM, Mandelker DL, Mehine M, Mukherjee S, Blanco-Heredia J, Orgera JJ, Nanjangud GJ, Baine MK, Aly RG, Sauter JL, Travis WD, Savari O, Moreira AL, Falcon CJ, Bodd FM, Wilson CE, Sienty JV, Manoj P, Sridhar H, Wang L, Choudhury NJ, Offin M, Yu HA, Quintanal-Villalonga A, Berger MF, Ladanyi M, Donoghue MTA, Reis-Filho JS, Rudin CM. Rekhtman N, et al. Among authors: manoj p. Cancer Discov. 2024 Aug 26. doi: 10.1158/2159-8290.CD-24-0286. Online ahead of print. Cancer Discov. 2024. PMID: 39185963
SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing.
Redin E, Sridhar H, Zhan YA, Pereira Mello B, Zhong H, Durani V, Sabet A, Manoj P, Linkov I, Qiu J, Koche RP, de Stanchina E, Astorkia M, Betel D, Quintanal-Villalonga Á, Rudin CM. Redin E, et al. Among authors: manoj p. J Hematol Oncol. 2024 Jul 30;17(1):58. doi: 10.1186/s13045-024-01572-3. J Hematol Oncol. 2024. PMID: 39080761 Free PMC article.
CDC7 inhibition impairs neuroendocrine transformation in lung and prostate tumors through MYC degradation.
Quintanal-Villalonga A, Kawasaki K, Redin E, Uddin F, Rakhade S, Durani V, Sabet A, Shafer M, Karthaus WR, Zaidi S, Zhan YA, Manoj P, Sridhar H, Kinyua D, Zhong H, Mello BP, Ciampricotti M, Bhanot UK, Linkov I, Qiu J, Patel RA, Morrissey C, Mehta S, Barnes J, Haffner MC, Socci ND, Koche RP, de Stanchina E, Molina-Pinelo S, Salehi S, Yu HA, Chan JM, Rudin CM. Quintanal-Villalonga A, et al. Among authors: manoj p. Signal Transduct Target Ther. 2024 Jul 26;9(1):189. doi: 10.1038/s41392-024-01908-y. Signal Transduct Target Ther. 2024. PMID: 39054323 Free PMC article.
Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers.
Quintanal-Villalonga A, Durani V, Sabet A, Redin E, Kawasaki K, Shafer M, Karthaus WR, Zaidi S, Zhan YA, Manoj P, Sridhar H, Shah NS, Chow A, Bhanot UK, Linkov I, Asher M, Yu HA, Qiu J, de Stanchina E, Patel RA, Morrissey C, Haffner MC, Koche RP, Sawyers CL, Rudin CM. Quintanal-Villalonga A, et al. Among authors: manoj p. Sci Transl Med. 2023 Aug 2;15(707):eadf7006. doi: 10.1126/scitranslmed.adf7006. Epub 2023 Aug 2. Sci Transl Med. 2023. PMID: 37531417 Free PMC article.
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