Okour M - Search Results

1

Pediatric Population Pharmacokinetic Modeling and Exposure-Response Analysis of Ambrisentan in Pulmonary Arterial Hypertension and Comparison With Adult Data.

Okour M, Thapar MM, Farrell C, Lukas MA, Beghetti M, Beerahee M. Okour M, et al. J Clin Pharmacol. 2023 May;63(5):593-603. doi: 10.1002/jcph.2199. Epub 2023 Jan 29. J Clin Pharmacol. 2023. PMID: 36579617

2

Orphan drug development: the increasing role of clinical pharmacology.

Ahmed MA, Okour M, Brundage R, Kartha RV. Ahmed MA, et al. Among authors: okour m. J Pharmacokinet Pharmacodyn. 2019 Oct;46(5):395-409. doi: 10.1007/s10928-019-09646-3. Epub 2019 Jul 23. J Pharmacokinet Pharmacodyn. 2019. PMID: 31338634 Review.

3

Mycophenolic Acid and Its Metabolites in Kidney Transplant Recipients: A Semimechanistic Enterohepatic Circulation Model to Improve Estimating Exposure.

Okour M, Jacobson PA, Ahmed MA, Israni AK, Brundage RC. Okour M, et al. J Clin Pharmacol. 2018 May;58(5):628-639. doi: 10.1002/jcph.1064. Epub 2018 Jan 12. J Clin Pharmacol. 2018. PMID: 29329489 Free PMC article.

4

A population analysis of the DGAT1 inhibitor GSK3008356 and its effect on endogenous and meal-induced triglyceride turnover in healthy subjects.

Okour M, Brigandi RA, Tenero D. Okour M, et al. Fundam Clin Pharmacol. 2019 Oct;33(5):567-580. doi: 10.1111/fcp.12455. Epub 2019 Mar 7. Fundam Clin Pharmacol. 2019. PMID: 30790345 Clinical Trial.

5

Population Pharmacokinetic Analysis of Fluticasone Furoate/Umeclidinium Bromide/Vilanterol in Patients with Chronic Obstructive Pulmonary Disease.

Mehta R, Farrell C, Hayes S, Birk R, Okour M, Lipson DA. Mehta R, et al. Among authors: okour m. Clin Pharmacokinet. 2020 Jan;59(1):67-79. doi: 10.1007/s40262-019-00794-w. Clin Pharmacokinet. 2020. PMID: 31321713 Free PMC article. Clinical Trial.

6

DosePredict: A Shiny Application for Generalized Pharmacokinetics-Based Dose Predictions.

Okour M. Okour M. J Clin Pharmacol. 2020 Nov;60(11):1502-1508. doi: 10.1002/jcph.1649. Epub 2020 Jun 15. J Clin Pharmacol. 2020. PMID: 32542731

7

Drug Combination Modeling: Methods and Applications in Drug Development.

Pearson RA, Wicha SG, Okour M. Pearson RA, et al. Among authors: okour m. J Clin Pharmacol. 2023 Feb;63(2):151-165. doi: 10.1002/jcph.2128. Epub 2022 Sep 11. J Clin Pharmacol. 2023. PMID: 36088583 Review.

8

A Randomized Study of Safety and Efficacy of Two Doses of Ambrisentan to Treat Pulmonary Arterial Hypertension in Pediatric Patients Aged 8 Years up to 18 Years.

Ivy D, Beghetti M, Juaneda-Simian E, Miller D, Lukas MA, Ioannou C, Okour M, Narita J, Berger RMF. Ivy D, et al. Among authors: okour m. J Pediatr X. 2020 Sep 22;5:100055. doi: 10.1016/j.ympdx.2020.100055. eCollection 2020 Spring. J Pediatr X. 2020. PMID: 37332660 Free PMC article.

9

A human microdose study of the antimalarial drug GSK3191607 in healthy volunteers.

Okour M, Derimanov G, Barnett R, Fernandez E, Ferrer S, Gresham S, Hossain M, Gamo FJ, Koh G, Pereira A, Rolfe K, Wong D, Young G, Rami H, Haselden J. Okour M, et al. Br J Clin Pharmacol. 2018 Mar;84(3):482-489. doi: 10.1111/bcp.13476. Epub 2017 Dec 29. Br J Clin Pharmacol. 2018. PMID: 29168205 Free PMC article. Clinical Trial.

10

First-in-Human Pharmacokinetics and Safety Study of GSK3008356, a Selective DGAT1 Inhibitor, in Healthy Volunteers.

Okour M, Gress A, Zhu X, Rieman D, Lickliter JD, Brigandi RA. Okour M, et al. Clin Pharmacol Drug Dev. 2019 Nov;8(8):1088-1099. doi: 10.1002/cpdd.691. Epub 2019 Apr 5. Clin Pharmacol Drug Dev. 2019. PMID: 30950565 Clinical Trial.

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