DeBosch BJ - Search Results

1

The tetraspanin transmembrane protein CD53 mediates dyslipidemia and integrates inflammatory and metabolic signaling in hepatocytes.

Higgins CB, Adams JA, Ward MH, Greenberg ZJ, Milewska M, Sun J, Zhang Y, Chiquetto Paracatu L, Dong Q, Ballentine S, Li W, Wandzik I, Schuettpelz LG, DeBosch BJ. Higgins CB, et al. Among authors: debosch bj. J Biol Chem. 2023 Feb;299(2):102835. doi: 10.1016/j.jbc.2022.102835. Epub 2022 Dec 27. J Biol Chem. 2023. PMID: 36581203 Free PMC article.

2

Insulin-like growth factor-1 effects on bovine retinal endothelial cell glucose transport: role of MAP kinase.

DeBosch BJ, Deo BK, Kumagai AK. DeBosch BJ, et al. J Neurochem. 2002 May;81(4):728-34. doi: 10.1046/j.1471-4159.2002.00848.x. J Neurochem. 2002. PMID: 12065632 Free article.

3

Glucose transporter 8 (GLUT8) mediates fructose-induced de novo lipogenesis and macrosteatosis.

DeBosch BJ, Chen Z, Saben JL, Finck BN, Moley KH. DeBosch BJ, et al. J Biol Chem. 2014 Apr 18;289(16):10989-10998. doi: 10.1074/jbc.M113.527002. Epub 2014 Feb 11. J Biol Chem. 2014. PMID: 24519932 Free PMC article.

4

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis.

DeBosch BJ, Heitmeier MR, Mayer AL, Higgins CB, Crowley JR, Kraft TE, Chi M, Newberry EP, Chen Z, Finck BN, Davidson NO, Yarasheski KE, Hruz PW, Moley KH. DeBosch BJ, et al. Sci Signal. 2016 Feb 23;9(416):ra21. doi: 10.1126/scisignal.aac5472. Sci Signal. 2016. PMID: 26905426 Free PMC article.

5

SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy.

Mayer AL, Higgins CB, Heitmeier MR, Kraft TE, Qian X, Crowley JR, Hyrc KL, Beatty WL, Yarasheski KE, Hruz PW, DeBosch BJ. Mayer AL, et al. Among authors: debosch bj. Sci Rep. 2016 Dec 6;6:38586. doi: 10.1038/srep38586. Sci Rep. 2016. PMID: 27922102 Free PMC article.

6

Enhanced Hepatic PPARα Activity Links GLUT8 Deficiency to Augmented Peripheral Fasting Responses in Male Mice.

Mayer AL, Zhang Y, Feng EH, Higgins CB, Adenekan O, Pietka TA, Beatty WL, DeBosch BJ. Mayer AL, et al. Among authors: debosch bj. Endocrinology. 2018 May 1;159(5):2110-2126. doi: 10.1210/en.2017-03150. Endocrinology. 2018. PMID: 29596655 Free PMC article.

7

TFEB-dependent induction of thermogenesis by the hepatocyte SLC2A inhibitor trehalose.

Zhang Y, Higgins CB, Mayer AL, Mysorekar IU, Razani B, Graham MJ, Hruz PW, DeBosch BJ. Zhang Y, et al. Among authors: debosch bj. Autophagy. 2018;14(11):1959-1975. doi: 10.1080/15548627.2018.1493044. Epub 2018 Aug 6. Autophagy. 2018. PMID: 29996716 Free PMC article.

8

Hepatocyte ALOXE3 is induced during adaptive fasting and enhances insulin sensitivity by activating hepatic PPARγ.

Higgins CB, Zhang Y, Mayer AL, Fujiwara H, Stothard AI, Graham MJ, Swarts BM, DeBosch BJ. Higgins CB, et al. Among authors: debosch bj. JCI Insight. 2018 Aug 23;3(16):e120794. doi: 10.1172/jci.insight.120794. eCollection 2018 Aug 23. JCI Insight. 2018. PMID: 30135298 Free PMC article.

9

Dietary restriction of iron availability attenuates UPEC pathogenesis in a mouse model of urinary tract infection.

Bauckman KA, Matsuda R, Higgins CB, DeBosch BJ, Wang C, Mysorekar IU. Bauckman KA, et al. Among authors: debosch bj. Am J Physiol Renal Physiol. 2019 May 1;316(5):F814-F822. doi: 10.1152/ajprenal.00133.2018. Epub 2019 Feb 6. Am J Physiol Renal Physiol. 2019. PMID: 30724105 Free PMC article.

10

Hepatic arginase 2 (Arg2) is sufficient to convey the therapeutic metabolic effects of fasting.

Zhang Y, Higgins CB, Fortune HM, Chen P, Stothard AI, Mayer AL, Swarts BM, DeBosch BJ. Zhang Y, et al. Among authors: debosch bj. Nat Commun. 2019 Apr 8;10(1):1587. doi: 10.1038/s41467-019-09642-8. Nat Commun. 2019. PMID: 30962478 Free PMC article.

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