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181 results

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Page 1
Engineering an inhibitor-resistant human CSF1R variant for microglia replacement.
Chadarevian JP, Lombroso SI, Peet GC, Hasselmann J, Tu C, Marzan DE, Capocchi J, Purnell FS, Nemec KM, Lahian A, Escobar A, England W, Chaluvadi S, O'Brien CA, Yaqoob F, Aisenberg WH, Porras-Paniagua M, Bennett ML, Davtyan H, Spitale RC, Blurton-Jones M, Bennett FC. Chadarevian JP, et al. J Exp Med. 2023 Mar 6;220(3):e20220857. doi: 10.1084/jem.20220857. Epub 2022 Dec 30. J Exp Med. 2023. PMID: 36584406 Free PMC article.
Perivascular signals drive microglial appetite.
O'Brien CA, Bennett FC. O'Brien CA, et al. Nat Neurosci. 2023 Mar;26(3):369-370. doi: 10.1038/s41593-023-01256-0. Nat Neurosci. 2023. PMID: 36747025 No abstract available.
Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism.
Profaci CP, Harvey SS, Bajc K, Zhang TZ, Jeffrey DA, Zhang AZ, Nemec KM, Davtyan H, O'Brien CA, McKinsey GL, Longworth A, McMullen TP, Capocchi JK, Gonzalez JG, Lawson DA, Arnold TD, Davalos D, Blurton-Jones M, Dabertrand F, Bennett FC, Daneman R. Profaci CP, et al. Among authors: o brien ca. Neuron. 2024 Sep 4;112(17):2910-2921.e7. doi: 10.1016/j.neuron.2024.07.015. Epub 2024 Aug 13. Neuron. 2024. PMID: 39142282 Free article.
Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutières Syndrome neuropathology.
Nemec KM, Uy G, Chaluvadi VS, Purnell FS, Elfayoumi B, O'Brien CA, Aisenberg WH, Lombroso SI, Guo X, Blank N, Oon CH, Yaqoob F, Temsamrit B, Rawat P, Thaiss CA, Wang Q, Bennett ML, Bennett FC. Nemec KM, et al. Among authors: o brien ca. bioRxiv [Preprint]. 2024 Sep 20:2024.09.18.613629. doi: 10.1101/2024.09.18.613629. bioRxiv. 2024. PMID: 39345609 Free PMC article. Preprint.
Tetraspanin CD53 Promotes Inflammation but Restrains Mucus Production in a Mouse Model of Allergic Airway Inflammation.
Hsu AT, Bugajev V, Gottschalk TA, Demkova L, Potuckova L, Draberova L, Bambouskova M, Hagemann P, O'Brien CA, Riecan M, Kuda O, Tsantikos E, Draber P, Wright MD, van Spriel AB, Hibbs ML, Halova I. Hsu AT, et al. Among authors: o brien ca. Allergy. 2024 Dec 9. doi: 10.1111/all.16426. Online ahead of print. Allergy. 2024. PMID: 39651606 No abstract available.
Single-Cell Transcriptomic Analysis Identifies Senescent Osteocytes That Trigger Bone Destruction in Breast Cancer Metastasis.
Kaur J, Adhikari M, Sabol HM, Anloague A, Khan S, Kurihara N, Diaz-delCastillo M, Andreasen CM, Barnes CL, Stambough JB, Palmieri M, Reyes-Castro O, Zarrer J, Taipaleenmäki H, Ambrogini E, Almeida M, O'Brien CA, Nookaw I, Delgado-Calle J. Kaur J, et al. Among authors: o brien ca. Cancer Res. 2024 Dec 2;84(23):3936-3952. doi: 10.1158/0008-5472.CAN-24-0857. Cancer Res. 2024. PMID: 39312185
Cancer drug-tolerant persister cells: from biological questions to clinical opportunities.
Russo M, Chen M, Mariella E, Peng H, Rehman SK, Sancho E, Sogari A, Toh TS, Balaban NQ, Batlle E, Bernards R, Garnett MJ, Hangauer M, Leucci E, Marine JC, O'Brien CA, Oren Y, Patton EE, Robert C, Rosenberg SM, Shen S, Bardelli A. Russo M, et al. Among authors: o brien ca. Nat Rev Cancer. 2024 Oct;24(10):694-717. doi: 10.1038/s41568-024-00737-z. Epub 2024 Sep 2. Nat Rev Cancer. 2024. PMID: 39223250 Review.
181 results