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Page 1
Diagnostic classification of childhood cancer using multiscale transcriptomics.
Comitani F, Nash JO, Cohen-Gogo S, Chang AI, Wen TT, Maheshwari A, Goyal B, Tio ES, Tabatabaei K, Mayoh C, Zhao R, Ho B, Brunga L, Lawrence JEG, Balogh P, Flanagan AM, Teichmann S, Huang A, Ramaswamy V, Hitzler J, Wasserman JD, Gladdy RA, Dickson BC, Tabori U, Cowley MJ, Behjati S, Malkin D, Villani A, Irwin MS, Shlien A. Comitani F, et al. Nat Med. 2023 Mar;29(3):656-666. doi: 10.1038/s41591-023-02221-x. Epub 2023 Mar 17. Nat Med. 2023. PMID: 36932241 Free PMC article.
The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations.
Villani A, Davidson S, Kanwar N, Lo WW, Li Y, Cohen-Gogo S, Fuligni F, Edward LM, Light N, Layeghifard M, Harripaul R, Waldman L, Gallinger B, Comitani F, Brunga L, Hayes R, Anderson ND, Ramani AK, Yuki KE, Blay S, Johnstone B, Inglese C, Hammad R, Goudie C, Shuen A, Wasserman JD, Venier RE, Eliou M, Lorenti M, Ryan CA, Braga M, Gloven-Brown M, Han J, Montero M, Spatare F, Whitlock JA, Scherer SW, Chun K, Somerville MJ, Hawkins C, Abdelhaleem M, Ramaswamy V, Somers GR, Kyriakopoulou L, Hitzler J, Shago M, Morgenstern DA, Tabori U, Meyn S, Irwin MS, Malkin D, Shlien A. Villani A, et al. Among authors: comitani f. Nat Cancer. 2023 Feb;4(2):203-221. doi: 10.1038/s43018-022-00474-y. Epub 2022 Dec 30. Nat Cancer. 2023. PMID: 36585449 Free PMC article.
Widespread hypertranscription in aggressive human cancers.
Zatzman M, Fuligni F, Ripsman R, Suwal T, Comitani F, Edward LM, Denroche R, Jang GH, Notta F, Gallinger S, Selvanathan SP, Toretsky JA, Hellmann MD, Tabori U, Huang A, Shlien A. Zatzman M, et al. Among authors: comitani f. Sci Adv. 2022 Nov 25;8(47):eabn0238. doi: 10.1126/sciadv.abn0238. Epub 2022 Nov 23. Sci Adv. 2022. PMID: 36417526 Free PMC article.
Extraction and high-throughput sequencing of oak heartwood DNA: Assessing the feasibility of genome-wide DNA methylation profiling.
Rossi F, Crnjar A, Comitani F, Feliciano R, Jahn L, Malim G, Southgate L, Kay E, Oakey R, Buggs R, Moir A, Kistler L, Rodriguez Mateos A, Molteni C, Schulz R. Rossi F, et al. Among authors: comitani f. PLoS One. 2021 Nov 18;16(11):e0254971. doi: 10.1371/journal.pone.0254971. eCollection 2021. PLoS One. 2021. PMID: 34793449 Free PMC article.
Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival.
Anderson ND, Babichev Y, Fuligni F, Comitani F, Layeghifard M, Venier RE, Dentro SC, Maheshwari A, Guram S, Wunker C, Thompson JD, Yuki KE, Hou H, Zatzman M, Light N, Bernardini MQ, Wunder JS, Andrulis IL, Ferguson P, Razak ARA, Swallow CJ, Dowling JJ, Al-Awar RS, Marcellus R, Rouzbahman M, Gerstung M, Durocher D, Alexandrov LB, Dickson BC, Gladdy RA, Shlien A. Anderson ND, et al. Among authors: comitani f. Nat Commun. 2021 Jul 23;12(1):4496. doi: 10.1038/s41467-021-24677-6. Nat Commun. 2021. PMID: 34301934 Free PMC article.
Single cell derived mRNA signals across human kidney tumors.
Young MD, Mitchell TJ, Custers L, Margaritis T, Morales-Rodriguez F, Kwakwa K, Khabirova E, Kildisiute G, Oliver TRW, de Krijger RR, van den Heuvel-Eibrink MM, Comitani F, Piapi A, Bugallo-Blanco E, Thevanesan C, Burke C, Prigmore E, Ambridge K, Roberts K, Braga FAV, Coorens THH, Del Valle I, Wilbrey-Clark A, Mamanova L, Stewart GD, Gnanapragasam VJ, Rampling D, Sebire N, Coleman N, Hook L, Warren A, Haniffa M, Kool M, Pfister SM, Achermann JC, He X, Barker RA, Shlien A, Bayraktar OA, Teichmann SA, Holstege FC, Meyer KB, Drost J, Straathof K, Behjati S. Young MD, et al. Among authors: comitani f. Nat Commun. 2021 Jun 23;12(1):3896. doi: 10.1038/s41467-021-23949-5. Nat Commun. 2021. PMID: 34162837 Free PMC article.
Defining an Optimal Metric for the Path Collective Variables.
Hovan L, Comitani F, Gervasio FL. Hovan L, et al. Among authors: comitani f. J Chem Theory Comput. 2019 Jan 8;15(1):25-32. doi: 10.1021/acs.jctc.8b00563. Epub 2018 Dec 5. J Chem Theory Comput. 2019. PMID: 30468578
A Multiscale Simulation Approach to Modeling Drug-Protein Binding Kinetics.
Haldar S, Comitani F, Saladino G, Woods C, van der Kamp MW, Mulholland AJ, Gervasio FL. Haldar S, et al. Among authors: comitani f. J Chem Theory Comput. 2018 Nov 13;14(11):6093-6101. doi: 10.1021/acs.jctc.8b00687. Epub 2018 Oct 2. J Chem Theory Comput. 2018. PMID: 30208708
19 results