Brandis G - Search Results

1

Antibiotic perseverance increases the risk of resistance development.

Brandis G, Larsson J, Elf J. Brandis G, et al. Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2216216120. doi: 10.1073/pnas.2216216120. Epub 2023 Jan 3. Proc Natl Acad Sci U S A. 2023. PMID: 36595701 Free PMC article.

2

Ciprofloxacin selects for RNA polymerase mutations with pleiotropic antibiotic resistance effects.

Pietsch F, Bergman JM, Brandis G, Marcusson LL, Zorzet A, Huseby DL, Hughes D. Pietsch F, et al. Among authors: brandis g. J Antimicrob Chemother. 2017 Jan;72(1):75-84. doi: 10.1093/jac/dkw364. Epub 2016 Sep 12. J Antimicrob Chemother. 2017. PMID: 27621175

3

Mutation Supply and Relative Fitness Shape the Genotypes of Ciprofloxacin-Resistant Escherichia coli.

Huseby DL, Pietsch F, Brandis G, Garoff L, Tegehall A, Hughes D. Huseby DL, et al. Among authors: brandis g. Mol Biol Evol. 2017 May 1;34(5):1029-1039. doi: 10.1093/molbev/msx052. Mol Biol Evol. 2017. PMID: 28087782 Free PMC article.

4

Antibiotic resistance by high-level intrinsic suppression of a frameshift mutation in an essential gene.

Huseby DL, Brandis G, Praski Alzrigat L, Hughes D. Huseby DL, et al. Among authors: brandis g. Proc Natl Acad Sci U S A. 2020 Feb 11;117(6):3185-3191. doi: 10.1073/pnas.1919390117. Epub 2020 Jan 28. Proc Natl Acad Sci U S A. 2020. PMID: 31992637 Free PMC article.

5

Population Bottlenecks Strongly Influence the Evolutionary Trajectory to Fluoroquinolone Resistance in Escherichia coli.

Garoff L, Pietsch F, Huseby DL, Lilja T, Brandis G, Hughes D. Garoff L, et al. Among authors: brandis g. Mol Biol Evol. 2020 Jun 1;37(6):1637-1646. doi: 10.1093/molbev/msaa032. Mol Biol Evol. 2020. PMID: 32031639 Free PMC article.

6

Resistance/fitness trade-off is a barrier to the evolution of MarR inactivation mutants in Escherichia coli.

Praski Alzrigat L, Huseby DL, Brandis G, Hughes D. Praski Alzrigat L, et al. Among authors: brandis g. J Antimicrob Chemother. 2021 Jan 1;76(1):77-83. doi: 10.1093/jac/dkaa417. J Antimicrob Chemother. 2021. PMID: 33089314 Free PMC article.

7

Mutant RNA polymerase can reduce susceptibility to antibiotics via ppGpp-independent induction of a stringent-like response.

Brandis G, Granström S, Leber AT, Bartke K, Garoff L, Cao S, Huseby DL, Hughes D. Brandis G, et al. J Antimicrob Chemother. 2021 Feb 11;76(3):606-615. doi: 10.1093/jac/dkaa469. J Antimicrob Chemother. 2021. PMID: 33221850 Free PMC article.

8

Expression of the qepA1 gene is induced under antibiotic exposure.

Brandis G, Gockel J, Garoff L, Guy L, Hughes D. Brandis G, et al. J Antimicrob Chemother. 2021 May 12;76(6):1433-1440. doi: 10.1093/jac/dkab045. J Antimicrob Chemother. 2021. PMID: 33608713 Free PMC article.

9

Fitness-compensatory mutations in rifampicin-resistant RNA polymerase.

Brandis G, Wrande M, Liljas L, Hughes D. Brandis G, et al. Mol Microbiol. 2012 Jul;85(1):142-51. doi: 10.1111/j.1365-2958.2012.08099.x. Epub 2012 May 31. Mol Microbiol. 2012. PMID: 22646234 Free article.

10

Genetic characterization of compensatory evolution in strains carrying rpoB Ser531Leu, the rifampicin resistance mutation most frequently found in clinical isolates.

Brandis G, Hughes D. Brandis G, et al. J Antimicrob Chemother. 2013 Nov;68(11):2493-7. doi: 10.1093/jac/dkt224. Epub 2013 Jun 11. J Antimicrob Chemother. 2013. PMID: 23759506

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