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Clonally expanded HIV-1 proviruses with 5'-leader defects can give rise to nonsuppressible residual viremia.
White JA, Wu F, Yasin S, Moskovljevic M, Varriale J, Dragoni F, Camilo-Contreras A, Duan J, Zheng MY, Tadzong NF, Patel HB, Quiambao JMC, Rhodehouse K, Zhang H, Lai J, Beg SA, Delannoy M, Kilcrease C, Hoffmann CJ, Poulin S, Chano F, Tremblay C, Cherian J, Barditch-Crovo P, Chida N, Moore RD, Summers MF, Siliciano RF, Siliciano JD, Simonetti FR. White JA, et al. Among authors: kilcrease c. J Clin Invest. 2023 Mar 15;133(6):e165245. doi: 10.1172/JCI165245. J Clin Invest. 2023. PMID: 36602866 Free PMC article.
Consensus recommendations for the use of novel antiretrovirals in persons with HIV who are heavily treatment-experienced and/or have multidrug-resistant HIV-1: Endorsed by the American Academy of HIV Medicine, American College of Clinical Pharmacy: An executive summary.
Cluck DB, Chastain DB, Murray M, Durham SH, Chahine EB, Derrick C, Dumond JB, Hester EK, Jeter SB, Johnson MD, Kilcrease C, Kufel WD, Kwong J, Ladak AF, Patel N, Pérez SE, Poe JB, Bolch C, Thomas I, Asiago-Reddy E, Short WR. Cluck DB, et al. Among authors: kilcrease c. Pharmacotherapy. 2024 May;44(5):354-359. doi: 10.1002/phar.2913. Pharmacotherapy. 2024. PMID: 38853605
Consensus recommendations for the use of novel antiretrovirals in persons with HIV who are heavily treatment-experienced and/or have multidrug-resistant HIV-1: Endorsed by the American Academy of HIV Medicine, American College of Clinical Pharmacy.
Cluck DB, Chastain DB, Murray M, Durham SH, Chahine EB, Derrick C, Dumond JB, Hester EK, Jeter SB, Johnson MD, Kilcrease C, Kufel WD, Kwong J, Ladak AF, Patel N, Pérez SE, Poe JB, Bolch C, Thomas I, Asiago-Reddy E, Short WR. Cluck DB, et al. Among authors: kilcrease c. Pharmacotherapy. 2024 May;44(5):360-382. doi: 10.1002/phar.2914. Pharmacotherapy. 2024. PMID: 38853601 Review.