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Integrated Single-Cell (Phospho-)Protein and RNA Detection Uncovers Phenotypic Characteristics and Active Signal Transduction of Human Antibody-Secreting Cells.
van Buijtenen E, Janssen W, Vink P, Habraken MJM, Wingens LJA, van Elsas A, Huck WTS, van Buggenum JAGL, van Eenennaam H. van Buijtenen E, et al. Among authors: janssen w. Mol Cell Proteomics. 2023 Feb;22(2):100492. doi: 10.1016/j.mcpro.2023.100492. Epub 2023 Jan 7. Mol Cell Proteomics. 2023. PMID: 36623694 Free PMC article.
Functional characterization of the selective pan-allele anti-SIRPα antibody ADU-1805 that blocks the SIRPα-CD47 innate immune checkpoint.
Voets E, Paradé M, Lutje Hulsik D, Spijkers S, Janssen W, Rens J, Reinieren-Beeren I, van den Tillaart G, van Duijnhoven S, Driessen L, Habraken M, van Zandvoort P, Kreijtz J, Vink P, van Elsas A, van Eenennaam H. Voets E, et al. Among authors: janssen w. J Immunother Cancer. 2019 Dec 4;7(1):340. doi: 10.1186/s40425-019-0772-0. J Immunother Cancer. 2019. PMID: 31801627 Free PMC article.
CXCL12 ameliorates neutrophilia and disease severity in SARS-CoV-2 infection.
Zheng J, Dhakal H, Qing E, Shrestha R, Geller AE, Morrissey SM, Saxena D, Hu X, Li H, Li H, Wilhelmsen K, Wendt LH, Klumpp K, Hume PS, Janssen WJ, Brody R, Palmer KE, Uriarte SM, Ten Eyck PP, Meyerholz DK, Merchant ML, McLeish K, Gallagher T, Huang J, Yan J, Perlman S. Zheng J, et al. Among authors: janssen wj. J Clin Invest. 2025 Jan 7:e188222. doi: 10.1172/JCI188222. Online ahead of print. J Clin Invest. 2025. PMID: 39773555 Free article.
Sialylated IgG induces the transcription factor REST in alveolar macrophages to protect against lung inflammation and severe influenza disease.
Chakraborty S, Cheng BY, Edwards DL, Gonzalez JC, Chiu DK, Zheng H, Scallan C, Guo X, Tan GS, Coffey GP, Conley PB, Hume PS, Janssen WJ, Byers DE, Mudd PA, Taubenberger J, Memoli M, Davis MM, Chua KF, Diamond MS, Andreakos E, Khatri P, Wang TT. Chakraborty S, et al. Among authors: janssen wj. Immunity. 2025 Jan 14;58(1):182-196.e10. doi: 10.1016/j.immuni.2024.10.002. Epub 2024 Nov 13. Immunity. 2025. PMID: 39541970 Free article.
Slamf7 is dispensable in mouse models of acute lung injury.
King EM, McClendon J, Trinh T, Matsuda JL, Lyn-Kew KH, McCubbrey AL, Mould KJ, Henson PM, Janssen WJ. King EM, et al. Among authors: janssen wj. ERJ Open Res. 2024 Oct 7;10(5):00345-2024. doi: 10.1183/23120541.00345-2024. eCollection 2024 Sep. ERJ Open Res. 2024. PMID: 39377087 Free PMC article.
Airway-derived emphysema-specific alveolar type II cells exhibit impaired regenerative potential in COPD.
Hu Y, Hu Q, Ansari M, Riemondy K, Pineda R, Sembrat J, Leme AS, Ngo K, Morgenthaler O, Ha K, Gao B, Janssen WJ, Basil MC, Kliment CR, Morrisey E, Lehmann M, Evans CM, Schiller HB, Königshoff M. Hu Y, et al. Among authors: janssen wj. Eur Respir J. 2024 Dec 5;64(6):2302071. doi: 10.1183/13993003.02071-2023. Print 2024 Dec. Eur Respir J. 2024. PMID: 39147413 Free PMC article.
655 results