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Design of Diverse Asymmetric Pockets in De Novo Homo-oligomeric Proteins.
Gerben SR, Borst AJ, Hicks DR, Moczygemba I, Feldman D, Coventry B, Yang W, Bera AK, Miranda M, Kang A, Nguyen H, Baker D. Gerben SR, et al. Among authors: moczygemba i. Biochemistry. 2023 Jan 17;62(2):358-368. doi: 10.1021/acs.biochem.2c00497. Epub 2023 Jan 10. Biochemistry. 2023. PMID: 36627259 Free PMC article.
Complete Combinatorial Mutational Enumeration of a protein functional site enables sequence-landscape mapping and identifies highly-mutated variants that retain activity.
Colom MS, Vucinic J, Adolf-Bryfogle J, Bowman JW, Verel S, Moczygemba I, Schiex T, Simoncini D, Bahl CD. Colom MS, et al. Among authors: moczygemba i. Res Sq [Preprint]. 2023 Sep 11:rs.3.rs-2248327. doi: 10.21203/rs.3.rs-2248327/v2. Res Sq. 2023. Update in: Protein Sci. 2024 Aug;33(8):e5109. doi: 10.1002/pro.5109 PMID: 36482980 Free PMC article. Updated. Preprint.