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The Oncology Biomarker Discovery framework reveals cetuximab and bevacizumab response patterns in metastatic colorectal cancer.
Ohnmacht AJ, Stahler A, Stintzing S, Modest DP, Holch JW, Westphalen CB, Hölzel L, Schübel MK, Galhoz A, Farnoud A, Ud-Dean M, Vehling-Kaiser U, Decker T, Moehler M, Heinig M, Heinemann V, Menden MP. Ohnmacht AJ, et al. Among authors: schubel mk. Nat Commun. 2023 Sep 4;14(1):5391. doi: 10.1038/s41467-023-41011-4. Nat Commun. 2023. PMID: 37666855 Free PMC article.
T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis.
Briukhovetska D, Suarez-Gosalvez J, Voigt C, Markota A, Giannou AD, Schübel M, Jobst J, Zhang T, Dörr J, Märkl F, Majed L, Müller PJ, May P, Gottschlich A, Tokarew N, Lücke J, Oner A, Schwerdtfeger M, Andreu-Sanz D, Grünmeier R, Seifert M, Michaelides S, Hristov M, König LM, Cadilha BL, Mikhaylov O, Anders HJ, Rothenfusser S, Flavell RA, Cerezo-Wallis D, Tejedo C, Soengas MS, Bald T, Huber S, Endres S, Kobold S. Briukhovetska D, et al. Among authors: schubel m. Immunity. 2023 Jan 10;56(1):143-161.e11. doi: 10.1016/j.immuni.2022.12.010. Immunity. 2023. PMID: 36630913 Free PMC article.
Journal Club.
Schübel M, Hantke K, Garcia Varo J, Seiffert-Störiko A, Schulz S, Neumann-Staubitz P, Gewering T, Kruck D, Schnell S, Steinert M. Schübel M, et al. Biospektrum (Heidelb). 2020;26(7):748-752. doi: 10.1007/s12268-020-1502-3. Epub 2020 Nov 25. Biospektrum (Heidelb). 2020. PMID: 33250578 Free PMC article. German. No abstract available.