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Transcriptional reprogramming restores UBE3A brain-wide and rescues behavioral phenotypes in an Angelman syndrome mouse model.
O'Geen H, Beitnere U, Garcia MS, Adhikari A, Cameron DL, Fenton TA, Copping NA, Deng P, Lock S, Halmai JANM, Villegas IJ, Liu J, Wang D, Fink KD, Silverman JL, Segal DJ. O'Geen H, et al. Among authors: lock s. Mol Ther. 2023 Apr 5;31(4):1088-1105. doi: 10.1016/j.ymthe.2023.01.013. Epub 2023 Jan 14. Mol Ther. 2023. PMID: 36641623 Free PMC article.
An in vivo Cell-Based Delivery Platform for Zinc Finger Artificial Transcription Factors in Pre-clinical Animal Models.
Deng P, Halmai JANM, Beitnere U, Cameron D, Martinez ML, Lee CC, Waldo JJ, Thongphanh K, Adhikari A, Copping N, Petkova SP, Lee RD, Lock S, Palomares M, O'Geen H, Carter J, Gonzalez CE, Buchanan FKB, Anderson JD, Fierro FA, Nolta JA, Tarantal AF, Silverman JL, Segal DJ, Fink KD. Deng P, et al. Among authors: lock s. Front Mol Neurosci. 2022 Jan 27;14:789913. doi: 10.3389/fnmol.2021.789913. eCollection 2021. Front Mol Neurosci. 2022. PMID: 35153670 Free PMC article.
Artificial escape from XCI by DNA methylation editing of the CDKL5 gene.
Halmai JANM, Deng P, Gonzalez CE, Coggins NB, Cameron D, Carter JL, Buchanan FKB, Waldo JJ, Lock SR, Anderson JD, O'Geen H, Segal DJ, Nolta J, Fink KD. Halmai JANM, et al. Nucleic Acids Res. 2020 Mar 18;48(5):2372-2387. doi: 10.1093/nar/gkz1214. Nucleic Acids Res. 2020. PMID: 31925439 Free PMC article.
Physical activity and sedentary behaviour interventions for people living with both frailty and multiple long-term conditions and their informal carers: a scoping review and stakeholder consultation.
Young HML, Henson J, Dempsey PC, Willis SA, Billany RE, Curtis F, Gray L, Greenwood S, Herring LY, Highton P, Kelsey RJ, Lock S, March DS, Patel K, Sargeant J, Sathanapally H, Sayer AA, Thomas M, Vadaszy N, Watson E, Yates T, Davies M. Young HML, et al. Among authors: lock s. Age Ageing. 2024 Nov 4;53(11):afae255. doi: 10.1093/ageing/afae255. Age Ageing. 2024. PMID: 39558868 Free PMC article. Review.
Variable-RBE-induced NTCP predictions for various side-effects following proton therapy for brain tumors - Identification of high-risk patients and risk mitigation.
Palkowitsch M, Kaufmann LM, Hennings F, Menkel S, Hahn C, Bensberg J, Lühr A, Seidlitz A, Troost EGC, Krause M, Löck S. Palkowitsch M, et al. Among authors: lock s. Radiother Oncol. 2025 Jan;202:110590. doi: 10.1016/j.radonc.2024.110590. Epub 2024 Oct 18. Radiother Oncol. 2025. PMID: 39427934 Free article.
428 results