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Effect of allogeneic adipose tissue-derived mesenchymal stromal cell treatment in chronic ischaemic heart failure with reduced ejection fraction - the SCIENCE trial.
Qayyum AA, van Klarenbosch B, Frljak S, Cerar A, Poglajen G, Traxler-Weidenauer D, Nadrowski P, Paitazoglou C, Vrtovec B, Bergmann MW, Chamuleau SAJ, Wojakowski W, Gyöngyösi M, Kraaijeveld A, Hansen KS, Vrangbaek K, Jørgensen E, Helqvist S, Joshi FR, Johansen EM, Follin B, Juhl M, Højgaard LD, Mathiasen AB, Ekblond A, Haack-Sørensen M, Kastrup J; SCIENCE Investigators. Qayyum AA, et al. Among authors: johansen em. Eur J Heart Fail. 2023 Apr;25(4):576-587. doi: 10.1002/ejhf.2772. Epub 2023 Jan 31. Eur J Heart Fail. 2023. PMID: 36644821 Free article. Clinical Trial.
Danish phase II trial using adipose tissue derived mesenchymal stromal cells for patients with ischaemic heart failure.
Qayyum AA, Mouridsen M, Nilsson B, Gustafsson I, Schou M, Nielsen OW, Hove JD, Mathiasen AB, Jørgensen E, Helqvist S, Joshi FR, Johansen EM, Follin B, Juhl M, Højgaard LD, Haack-Sørensen M, Ekblond A, Kastrup J. Qayyum AA, et al. Among authors: johansen em. ESC Heart Fail. 2023 Apr;10(2):1170-1183. doi: 10.1002/ehf2.14281. Epub 2023 Jan 13. ESC Heart Fail. 2023. PMID: 36638837 Free PMC article. Clinical Trial.
Rationale and Design of the First Double-Blind, Placebo-Controlled Trial with Allogeneic Adipose Tissue-Derived Stromal Cell Therapy in Patients with Ischemic Heart Failure: A Phase II Danish Multicentre Study.
Kastrup J, Schou M, Gustafsson I, Nielsen OW, Møgelvang R, Kofoed KF, Kragelund C, Hove JD, Fabricius-Bjerre A, Heitman M, Haack-Sørensen M, Lund LD, Johansen EM, Qayyum AA, Mathiasen AB, Ekblond A. Kastrup J, et al. Among authors: johansen em. Stem Cells Int. 2017;2017:8506370. doi: 10.1155/2017/8506370. Epub 2017 Sep 19. Stem Cells Int. 2017. PMID: 29056973 Free PMC article.