Yao D - Search Results

1

Identification of LRRK2 Inhibitors through Computational Drug Repurposing.

Tan S, Lu R, Yao D, Wang J, Gao P, Xie G, Liu H, Yao X. Tan S, et al. Among authors: yao x, yao d. ACS Chem Neurosci. 2023 Feb 1;14(3):481-493. doi: 10.1021/acschemneuro.2c00672. Epub 2023 Jan 17. ACS Chem Neurosci. 2023. PMID: 36649061

2

Upgrade of chrysomycin A as a novel topoisomerase II inhibitor to curb KRAS-mutant lung adenocarcinoma progression.

Zhang J, Liu P, Chen J, Yao D, Liu Q, Zhang J, Zhang HW, Leung EL, Yao XJ, Liu L. Zhang J, et al. Among authors: yao d, yao xj. Pharmacol Res. 2023 Jan;187:106565. doi: 10.1016/j.phrs.2022.106565. Epub 2022 Nov 19. Pharmacol Res. 2023. PMID: 36414124 Free article.

3

Fragment-based design, synthesis and biological evaluation of theophylline derivatives as ATAD2 inhibitors in BT-549 cells.

Yao D, You J, Yang X, Zhang J, Yao X. Yao D, et al. Among authors: yao x. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2242601. doi: 10.1080/14756366.2023.2242601. J Enzyme Inhib Med Chem. 2023. PMID: 37533352 Free PMC article.

4

Design, synthesis and biological evaluation of 2-indolinone derivatives as PAK1 inhibitors in MDA-MB-231 cells.

Yao D, Ruhan A, Jiang J, Huang J, Wang J, Han W. Yao D, et al. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127355. doi: 10.1016/j.bmcl.2020.127355. Epub 2020 Jun 20. Bioorg Med Chem Lett. 2020. PMID: 32738980

5

Design, synthesis and biological evaluation of dual mTOR/HDAC6 inhibitors in MDA-MB-231 cells.

Yao D, Jiang J, Zhang H, Huang Y, Huang J, Wang J. Yao D, et al. Bioorg Med Chem Lett. 2021 Sep 1;47:128204. doi: 10.1016/j.bmcl.2021.128204. Epub 2021 Jun 14. Bioorg Med Chem Lett. 2021. PMID: 34139324

6

Dual-target inhibitors of PARP1 in cancer therapy: A drug discovery perspective.

Zhang J, Zhang J, Li H, Chen L, Yao D. Zhang J, et al. Among authors: yao d. Drug Discov Today. 2023 Jul;28(7):103607. doi: 10.1016/j.drudis.2023.103607. Epub 2023 May 3. Drug Discov Today. 2023. PMID: 37146962 Review.

7

ATPase family AAA domain-containing protein 2 (ATAD2): From an epigenetic modulator to cancer therapeutic target.

Fu J, Zhang J, Chen X, Liu Z, Yang X, He Z, Hao Y, Liu B, Yao D. Fu J, et al. Among authors: yao d. Theranostics. 2023 Jan 1;13(2):787-809. doi: 10.7150/thno.78840. eCollection 2023. Theranostics. 2023. PMID: 36632213 Free PMC article. Review.

8

Catalytic Atroposelective Synthesis of Axially Chiral Azomethine Imines and Neuroprotective Activity Evaluation.

Yang QQ, Chen C, Yao D, Liu W, Liu B, Zhou J, Pan D, Peng C, Zhan G, Han B. Yang QQ, et al. Among authors: yao d. Angew Chem Int Ed Engl. 2024 Jan 25;63(5):e202312663. doi: 10.1002/anie.202312663. Epub 2023 Dec 11. Angew Chem Int Ed Engl. 2024. PMID: 38032817

9

Design, synthesis and biological evaluation of 1H-pyrazolo [3,4-d]pyrimidine derivatives as PAK1 inhibitors that trigger apoptosis, ER stress and anti-migration effect in MDA-MB-231 cells.

Zhang J, Zou L, Tang P, Pan D, He Z, Yao D. Zhang J, et al. Among authors: yao d. Eur J Med Chem. 2020 May 15;194:112220. doi: 10.1016/j.ejmech.2020.112220. Epub 2020 Mar 12. Eur J Med Chem. 2020. PMID: 32222676

10

A practical strategy to develop isoform-selective near-infrared fluorescent probes for human cytochrome P450 enzymes.

Feng L, Tian X, Yao D, Yu Z, Huo X, Tian Z, Ning J, Cui J, James TD, Ma X. Feng L, et al. Among authors: yao d. Acta Pharm Sin B. 2022 Apr;12(4):1976-1986. doi: 10.1016/j.apsb.2021.11.019. Epub 2021 Nov 25. Acta Pharm Sin B. 2022. PMID: 35847500 Free PMC article.

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