Pinedo HM - Search Results

1

Uridine-induced hypothermia in mice and rats in relation to plasma and tissue levels of uridine and its metabolites.

Peters GJ, van Groeningen CJ, Laurensse EJ, Lankelma J, Leyva A, Pinedo HM. Peters GJ, et al. Among authors: pinedo hm. Cancer Chemother Pharmacol. 1987;20(2):101-8. doi: 10.1007/BF00253962. Cancer Chemother Pharmacol. 1987. PMID: 3664929

2

A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa.

Peters GJ, van Groeningen CJ, Laurensse EJ, Pinedo HM. Peters GJ, et al. Among authors: pinedo hm. Cancer. 1991 Nov 1;68(9):1903-9. doi: 10.1002/1097-0142(19911101)68:9<1903::aid-cncr2820680910>3.0.co;2-9. Cancer. 1991. PMID: 1717130

3

In vitro and in vivo studies on the combination of Brequinar sodium (DUP-785; NSC 368390) with 5-fluorouracil; effects of uridine.

Peters GJ, Kraal I, Pinedo HM. Peters GJ, et al. Among authors: pinedo hm. Br J Cancer. 1992 Feb;65(2):229-33. doi: 10.1038/bjc.1992.46. Br J Cancer. 1992. PMID: 1739622 Free PMC article.

4

Measurement of in vitro cellular pharmacokinetics of 5-fluorouracil in human and rat cancer cell lines and rat hepatocytes using a flow-through system.

Spoelstra EC, Pinedo HM, Dekker H, Peters GJ, Lankelma J. Spoelstra EC, et al. Among authors: pinedo hm. Cancer Chemother Pharmacol. 1991;27(4):320-5. doi: 10.1007/BF00685119. Cancer Chemother Pharmacol. 1991. PMID: 1998989

5

Clinical and pharmacologic study of orally administered uridine.

van Groeningen CJ, Peters GJ, Nadal JC, Laurensse E, Pinedo HM. van Groeningen CJ, et al. Among authors: pinedo hm. J Natl Cancer Inst. 1991 Mar 20;83(6):437-41. doi: 10.1093/jnci/83.6.437. J Natl Cancer Inst. 1991. PMID: 1999851

6

Retention of in vivo antipyrimidine effects of Brequinar sodium (DUP-785; NSC 368390) in murine liver, bone marrow and colon cancer.

Peters GJ, Nadal JC, Laurensse EJ, de Kant E, Pinedo HM. Peters GJ, et al. Among authors: pinedo hm. Biochem Pharmacol. 1990 Jan 1;39(1):135-44. doi: 10.1016/0006-2952(90)90657-7. Biochem Pharmacol. 1990. PMID: 2153375

7

In vivo inhibition of the pyrimidine de novo enzyme dihydroorotic acid dehydrogenase by brequinar sodium (DUP-785; NSC 368390) in mice and patients.

Peters GJ, Schwartsmann G, Nadal JC, Laurensse EJ, van Groeningen CJ, van der Vijgh WJ, Pinedo HM. Peters GJ, et al. Among authors: pinedo hm. Cancer Res. 1990 Aug 1;50(15):4644-9. Cancer Res. 1990. PMID: 2164443

8

Enhanced therapeutic efficacy of 5'deoxy-5-fluorouridine in 5-fluorouracil resistant head and neck tumours in relation to 5-fluorouracil metabolising enzymes.

Peters GJ, Braakhuis BJ, de Bruijn EA, Laurensse EJ, van Walsum M, Pinedo HM. Peters GJ, et al. Among authors: pinedo hm. Br J Cancer. 1989 Mar;59(3):327-34. doi: 10.1038/bjc.1989.65. Br J Cancer. 1989. PMID: 2522792 Free PMC article.

9

Schedule-dependency of in vivo modulation of 5-fluorouracil by leucovorin and uridine in murine colon carcinoma.

Nadal JC, van Groeningen CJ, Pinedo HM, Peters GJ. Nadal JC, et al. Among authors: pinedo hm. Invest New Drugs. 1989 Jul;7(2-3):163-72. doi: 10.1007/BF00170853. Invest New Drugs. 1989. PMID: 2793368

10

DUP 785 (NSC 368390): schedule-dependency of growth-inhibitory and antipyrimidine effects.

Schwartsmann G, Peters GJ, Laurensse E, de Waal FC, Loonen AH, Leyva A, Pinedo HM. Schwartsmann G, et al. Among authors: pinedo hm. Biochem Pharmacol. 1988 Sep 1;37(17):3257-66. doi: 10.1016/0006-2952(88)90636-3. Biochem Pharmacol. 1988. PMID: 2840910

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