Mach RH - Search Results

1

Identification and Characterization of ML321: A Novel and Highly Selective D₂ Dopamine Receptor Antagonist with Efficacy in Animal Models That Predict Atypical Antipsychotic Activity.

Free RB, Nilson AN, Boldizsar NM, Doyle TB, Rodriguiz RM, Pogorelov VM, Machino M, Lee KH, Bertz JW, Xu J, Lim HD, Dulcey AE, Mach RH, Woods JH, Lane JR, Shi L, Marugan JJ, Wetsel WC, Sibley DR. Free RB, et al. Among authors: mach rh. ACS Pharmacol Transl Sci. 2022 Dec 30;6(1):151-170. doi: 10.1021/acsptsci.2c00202. eCollection 2023 Jan 13. ACS Pharmacol Transl Sci. 2022. PMID: 36654757 Free PMC article.

2

Synthesis and in vitro binding of N-phenyl piperazine analogs as potential dopamine D3 receptor ligands.

Chu W, Tu Z, McElveen E, Xu J, Taylor M, Luedtke RR, Mach RH. Chu W, et al. Among authors: mach rh. Bioorg Med Chem. 2005 Jan 3;13(1):77-87. doi: 10.1016/j.bmc.2004.09.054. Bioorg Med Chem. 2005. PMID: 15582454

3

Synthesis and characterization of selective dopamine D2 receptor antagonists.

Vangveravong S, McElveen E, Taylor M, Xu J, Tu Z, Luedtke RR, Mach RH. Vangveravong S, et al. Among authors: mach rh. Bioorg Med Chem. 2006 Feb 1;14(3):815-25. doi: 10.1016/j.bmc.2005.09.008. Epub 2005 Nov 8. Bioorg Med Chem. 2006. PMID: 16288878

4

[3H]N-[4-(3,4-dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl)butyl]-2-methoxy-5-methylbenzamide: a novel sigma-2 receptor probe.

Xu J, Tu Z, Jones LA, Vangveravong S, Wheeler KT, Mach RH. Xu J, et al. Among authors: mach rh. Eur J Pharmacol. 2005 Nov 21;525(1-3):8-17. doi: 10.1016/j.ejphar.2005.09.063. Epub 2005 Nov 10. Eur J Pharmacol. 2005. PMID: 16289030

5

Synthesis and in vivo evaluation of 2 high-affinity 76Br-labeled sigma2-receptor ligands.

Rowland DJ, Tu Z, Xu J, Ponde D, Mach RH, Welch MJ. Rowland DJ, et al. Among authors: mach rh. J Nucl Med. 2006 Jun;47(6):1041-8. J Nucl Med. 2006. PMID: 16741315 Free article.

6

Synthesis of N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl carbamate analogs as sigma2 receptor ligands.

Vangveravong S, Xu J, Zeng C, Mach RH. Vangveravong S, et al. Among authors: mach rh. Bioorg Med Chem. 2006 Oct 15;14(20):6988-97. doi: 10.1016/j.bmc.2006.06.028. Epub 2006 Jul 11. Bioorg Med Chem. 2006. PMID: 16837201

7

Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis.

Zhou D, Chu W, Rothfuss J, Zeng C, Xu J, Jones L, Welch MJ, Mach RH. Zhou D, et al. Among authors: mach rh. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5041-6. doi: 10.1016/j.bmcl.2006.07.045. Epub 2006 Aug 7. Bioorg Med Chem Lett. 2006. PMID: 16891117

8

[(3)H]4-(Dimethylamino)-N-[4-(4-(2-methoxyphenyl)piperazin- 1-yl)butyl]benzamide, a selective radioligand for dopamine D(3) receptors. I. In vitro characterization.

Xu J, Chu W, Tu Z, Jones LA, Luedtke RR, Perlmutter JS, Mintun MA, Mach RH. Xu J, et al. Among authors: mach rh. Synapse. 2009 Sep;63(9):717-28. doi: 10.1002/syn.20652. Synapse. 2009. PMID: 19425052 Free PMC article.

9

Carbon-11 labeled papaverine as a PET tracer for imaging PDE10A: radiosynthesis, in vitro and in vivo evaluation.

Tu Z, Xu J, Jones LA, Li S, Mach RH. Tu Z, et al. Among authors: mach rh. Nucl Med Biol. 2010 May;37(4):509-16. doi: 10.1016/j.nucmedbio.2009.12.012. Epub 2010 Mar 6. Nucl Med Biol. 2010. PMID: 20447563 Free PMC article.

10

Synthesis and characterization of selective dopamine D2 receptor antagonists. 2. Azaindole, benzofuran, and benzothiophene analogs of L-741,626.

Vangveravong S, Taylor M, Xu J, Cui J, Calvin W, Babic S, Luedtke RR, Mach RH. Vangveravong S, et al. Among authors: mach rh. Bioorg Med Chem. 2010 Jul 15;18(14):5291-300. doi: 10.1016/j.bmc.2010.05.052. Epub 2010 May 24. Bioorg Med Chem. 2010. PMID: 20542439 Free PMC article.

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