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Gene-by-gene screen of the unknown proteins encoded on Plasmodium falciparum chromosome 3.
Kimmel J, Schmitt M, Sinner A, Jansen PWTC, Mainye S, Ramón-Zamorano G, Toenhake CG, Wichers-Misterek JS, Cronshagen J, Sabitzki R, Mesén-Ramírez P, Behrens HM, Bártfai R, Spielmann T. Kimmel J, et al. Among authors: mesen ramirez p. Cell Syst. 2023 Jan 18;14(1):9-23.e7. doi: 10.1016/j.cels.2022.12.001. Cell Syst. 2023. PMID: 36657393 Free article.
Identification of new PNEPs indicates a substantial non-PEXEL exportome and underpins common features in Plasmodium falciparum protein export.
Heiber A, Kruse F, Pick C, Grüring C, Flemming S, Oberli A, Schoeler H, Retzlaff S, Mesén-Ramírez P, Hiss JA, Kadekoppala M, Hecht L, Holder AA, Gilberger TW, Spielmann T. Heiber A, et al. PLoS Pathog. 2013;9(8):e1003546. doi: 10.1371/journal.ppat.1003546. Epub 2013 Aug 8. PLoS Pathog. 2013. PMID: 23950716 Free PMC article.
A genetic system to study Plasmodium falciparum protein function.
Birnbaum J, Flemming S, Reichard N, Soares AB, Mesén-Ramírez P, Jonscher E, Bergmann B, Spielmann T. Birnbaum J, et al. Nat Methods. 2017 Apr;14(4):450-456. doi: 10.1038/nmeth.4223. Epub 2017 Mar 13. Nat Methods. 2017. PMID: 28288121
A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites.
Birnbaum J, Scharf S, Schmidt S, Jonscher E, Hoeijmakers WAM, Flemming S, Toenhake CG, Schmitt M, Sabitzki R, Bergmann B, Fröhlke U, Mesén-Ramírez P, Blancke Soares A, Herrmann H, Bártfai R, Spielmann T. Birnbaum J, et al. Among authors: mesen ramirez p. Science. 2020 Jan 3;367(6473):51-59. doi: 10.1126/science.aax4735. Science. 2020. PMID: 31896710
Characterization of Apicomplexan Amino Acid Transporters (ApiATs) in the Malaria Parasite Plasmodium falciparum.
Wichers JS, van Gelder C, Fuchs G, Ruge JM, Pietsch E, Ferreira JL, Safavi S, von Thien H, Burda PC, Mesén-Ramirez P, Spielmann T, Strauss J, Gilberger TW, Bachmann A. Wichers JS, et al. Among authors: mesen ramirez p. mSphere. 2021 Dec 22;6(6):e0074321. doi: 10.1128/mSphere.00743-21. Epub 2021 Nov 10. mSphere. 2021. PMID: 34756057 Free PMC article.
The parasitophorous vacuole nutrient channel is critical for drug access in malaria parasites and modulates the artemisinin resistance fitness cost.
Mesén-Ramírez P, Bergmann B, Elhabiri M, Zhu L, von Thien H, Castro-Peña C, Gilberger TW, Davioud-Charvet E, Bozdech Z, Bachmann A, Spielmann T. Mesén-Ramírez P, et al. Cell Host Microbe. 2021 Dec 8;29(12):1774-1787.e9. doi: 10.1016/j.chom.2021.11.002. Epub 2021 Dec 3. Cell Host Microbe. 2021. PMID: 34863371 Free article.
PMRT1, a Plasmodium-Specific Parasite Plasma Membrane Transporter, Is Essential for Asexual and Sexual Blood Stage Development.
Wichers JS, Mesén-Ramírez P, Fuchs G, Yu-Strzelczyk J, Stäcker J, von Thien H, Alder A, Henshall I, Liffner B, Nagel G, Löw C, Wilson D, Spielmann T, Gao S, Gilberger TW, Bachmann A, Strauss J. Wichers JS, et al. Among authors: mesen ramirez p. mBio. 2022 Apr 26;13(2):e0062322. doi: 10.1128/mbio.00623-22. Epub 2022 Apr 11. mBio. 2022. PMID: 35404116 Free PMC article.
17 results