Patsenker L - Search Results

1

Effect of Solubilizing Group on the Antibacterial Activity of Heptamethine Cyanine Photosensitizers.

Semenova O, Kobzev D, Hovor I, Atrash M, Nakonechny F, Kulyk O, Bazylevich A, Gellerman G, Patsenker L. Semenova O, et al. Among authors: patsenker l. Pharmaceutics. 2023 Jan 11;15(1):247. doi: 10.3390/pharmaceutics15010247. Pharmaceutics. 2023. PMID: 36678875 Free PMC article.

2

Synthesis and biological evaluation of theranostic Trastuzumab-SN38 conjugate for Near-IR fluorescence imaging and targeted therapy of HER2+ breast cancer.

Kobzev D, Prasad C, Walunj D, Gotman H, Semenova O, Bazylevich A, Patsenker L, Gellerman G. Kobzev D, et al. Among authors: patsenker l. Eur J Med Chem. 2023 Apr 5;252:115298. doi: 10.1016/j.ejmech.2023.115298. Epub 2023 Mar 22. Eur J Med Chem. 2023. PMID: 36966651

3

Synthesis and anticancer properties of novel dolastatin 10 analogs featuring five-membered heterocyclic rings with a linkable group at the C-terminus.

Panja A, Sharma V, Mitra P, Bazylevich A, Drori C, Kayet A, Tobi D, Patsenker L, Firer M, Gellerman G. Panja A, et al. Among authors: patsenker l. Bioorg Med Chem. 2024 Jul 15;109:117794. doi: 10.1016/j.bmc.2024.117794. Epub 2024 Jun 12. Bioorg Med Chem. 2024. PMID: 38875875

4

Novel Cyclic Peptide-Drug Conjugate P6-SN38 Toward Targeted Treatment of EGFR Overexpressed Non-Small Cell Lung Cancer.

Bazylevich A, Miller A, Tkachenko I, Merlani M, Patsenker L, Gellerman G, Lubin BCR. Bazylevich A, et al. Among authors: patsenker l. Pharmaceutics. 2024 Dec 19;16(12):1613. doi: 10.3390/pharmaceutics16121613. Pharmaceutics. 2024. PMID: 39771591 Free PMC article.

5

Sonodynamic Therapy for HER2+ Breast Cancer with Iodinated Heptamethine Cyanine-Trastuzumab Conjugate.

Kobzev D, Semenova O, Aviel-Ronen S, Kulyk O, Carmieli R, Mirzabekov T, Gellerman G, Patsenker L. Kobzev D, et al. Among authors: patsenker l. Int J Mol Sci. 2024 Sep 21;25(18):10137. doi: 10.3390/ijms251810137. Int J Mol Sci. 2024. PMID: 39337633 Free PMC article.

6

Novel Cyclic Peptides for Targeting EGFR and EGRvIII Mutation for Drug Delivery.

Furman O, Zaporozhets A, Tobi D, Bazylevich A, Firer MA, Patsenker L, Gellerman G, Lubin BCR. Furman O, et al. Among authors: patsenker l. Pharmaceutics. 2022 Jul 20;14(7):1505. doi: 10.3390/pharmaceutics14071505. Pharmaceutics. 2022. PMID: 35890400 Free PMC article.

7

Antibody guided activatable NIR photosensitizing system for fluorescently monitored photodynamic therapy with reduced side effects.

Thankarajan E, Tuchinsky H, Aviel-Ronen S, Bazylevich A, Gellerman G, Patsenker L. Thankarajan E, et al. Among authors: patsenker l. J Control Release. 2022 Mar;343:506-517. doi: 10.1016/j.jconrel.2022.02.008. Epub 2022 Feb 9. J Control Release. 2022. PMID: 35150812

8

A novel, dual action chimera comprising DNA methylating agent and near-IR xanthene-cyanine photosensitizer for combined anticancer therapy.

Thankarajan E, Walunj D, Bazylevich A, Prasad C, Hesin A, Patsenker L, Gellerman G. Thankarajan E, et al. Among authors: patsenker l. Photodiagnosis Photodyn Ther. 2022 Mar;37:102722. doi: 10.1016/j.pdpdt.2022.102722. Epub 2022 Jan 13. Photodiagnosis Photodyn Ther. 2022. PMID: 35032703

9

Discovery of Dolastatinol: A Synthetic Analog of Dolastatin 10 and Low Nanomolar Inhibitor of Tubulin Polymerization.

Gutman H, Bazylevich A, Prasad C, Dorfman O, Hesin A, Marks V, Patsenker L, Gellerman G. Gutman H, et al. Among authors: patsenker l. ACS Med Chem Lett. 2021 Sep 7;12(10):1596-1604. doi: 10.1021/acsmedchemlett.1c00432. eCollection 2021 Oct 14. ACS Med Chem Lett. 2021. PMID: 34676042 Free PMC article.

10

Targeted methylation facilitates DNA double strand breaks and enhances cancer suppression: A DNA intercalating/methylating dual-action chimera Amonafidazene.

Walunj D, Thankarajan E, Prasad C, Tuchinsky H, Baldan S, Sherman MY, Patsenker L, Gellerman G. Walunj D, et al. Among authors: patsenker l. Eur J Med Chem. 2021 Dec 5;225:113811. doi: 10.1016/j.ejmech.2021.113811. Epub 2021 Aug 31. Eur J Med Chem. 2021. PMID: 34507011

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