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Page 1
Bivalent intra-spike binding provides durability against emergent Omicron lineages: Results from a global consortium.
Callaway HM, Hastie KM, Schendel SL, Li H, Yu X, Shek J, Buck T, Hui S, Bedinger D, Troup C, Dennison SM, Li K, Alpert MD, Bailey CC, Benzeno S, Bonnevier JL, Chen JQ, Chen C, Cho H, Crompton PD, Dussupt V, Entzminger KC, Ezzyat Y, Fleming JK, Geukens N, Gilbert AE, Guan Y, Han X, Harvey CJ, Hatler JM, Howie B, Hu C, Huang A, Imbrechts M, Jin A, Kamachi N, Keitany G, Klinger M, Kolls JK, Krebs SJ, Li T, Luo F, Maruyama T, Meehl MA, Mendez-Rivera L, Musa A, Okumura CJ, Rubin BER, Sato AK, Shen M, Singh A, Song S, Tan J, Trimarchi JM, Upadhyay DP, Wang Y, Yu L, Yuan TZ, Yusko E, Peters B, Tomaras G, Saphire EO. Callaway HM, et al. Among authors: bedinger d. Cell Rep. 2023 Jan 31;42(1):112014. doi: 10.1016/j.celrep.2023.112014. Epub 2023 Jan 12. Cell Rep. 2023. PMID: 36681898 Free PMC article.
Coronavirus Immunotherapeutic Consortium Database.
Mahita J, Ha B, Gambiez A, Schendel SL, Li H, Hastie KM, Dennison SM, Li K, Kuzmina N, Periasamy S, Bukreyev A, Munt JE, Osei-Twum M, Atyeo C, Overton JA, Vita R, Guzman-Orozco H, Mendes M, Kojima M, Halfmann PJ, Kawaoka Y, Alter G, Gagnon L, Baric RS, Tomaras GD, Germann T, Bedinger D, Greenbaum JA, Saphire EO, Peters B. Mahita J, et al. Among authors: bedinger d. Database (Oxford). 2023 Feb 10;2023:baac112. doi: 10.1093/database/baac112. Database (Oxford). 2023. PMID: 36763096 Free PMC article.
Cryptic-site-specific antibodies to the SARS-CoV-2 receptor binding domain can retain functional binding affinity to spike variants.
Li K, Huntwork RHC, Horn GQ, Abraha M, Hastie KM, Li H, Rayaprolu V, Olmedillas E, Feeney E, Cronin K, Schendel SL, Heise M, Bedinger D, Mattocks MD, Baric RS, Alam SM, Ollmann Saphire E, Tomaras GD, Dennison SM. Li K, et al. Among authors: bedinger d. J Virol. 2023 Dec 21;97(12):e0107023. doi: 10.1128/jvi.01070-23. Epub 2023 Nov 29. J Virol. 2023. PMID: 38019013 Free PMC article.
Widespread monoclonal IgE antibody convergence to an immunodominant, proanaphylactic Ara h 2 epitope in peanut allergy.
Croote D, Wong JJW, Pecalvel C, Leveque E, Casanovas N, Kamphuis JBJ, Creeks P, Romero J, Sohail S, Bedinger D, Nadeau KC, Chinthrajah RS, Reber LL, Lowman HB. Croote D, et al. Among authors: bedinger d. J Allergy Clin Immunol. 2024 Jan;153(1):182-192.e7. doi: 10.1016/j.jaci.2023.08.035. Epub 2023 Sep 23. J Allergy Clin Immunol. 2024. PMID: 37748654 Free PMC article.
AIntibody: an experimentally validated in silico antibody discovery design challenge.
Erasmus MF, Spector L, Ferrara F, DiNiro R, Pohl TJ, Perea-Schmittle K, Wang W, Tessier PM, Richardson C, Turner L, Kumar S, Bedinger D, Sormanni P, Fernández-Quintero ML, Ward AB, Loeffler JR, Swanson OM, Deane CM, Raybould MIJ, Evers A, Sellmann C, Bachas S, Ruffolo J, Nastri HG, Ramesh K, Sørensen J, Croasdale-Wood R, Hijano O, Leal-Lopes C, Shahsavarian M, Qiu Y, Marcatili P, Vernet E, Akbar R, Friedensohn S, Wagner R, Kurella VB, Malhotra S, Kumar S, Kidger P, Almagro JC, Furfine E, Stanton M, Graff CP, Villalba SD, Tomszak F, Teixeira AAR, Hopkins E, Dovner M, D'Angelo S, Bradbury ARM. Erasmus MF, et al. Among authors: bedinger d. Nat Biotechnol. 2024 Nov;42(11):1637-1642. doi: 10.1038/s41587-024-02469-9. Nat Biotechnol. 2024. PMID: 39496931 No abstract available.
Characterization of two affinity matured Anti-Yersinia pestis F1 human antibodies with medical countermeasure potential.
Velappan N, Biryukov SS, Rill NO, Klimko CP, Rosario-Acevedo R, Shoe JL, Hunter M, Dankmeyer JL, Fetterer DP, Bedinger D, Phipps ME, Watt AJ, Abergel RJ, Dichosa A, Kozimor SA, Cote CK, Lillo AM. Velappan N, et al. Among authors: bedinger d. PLoS One. 2024 Jul 2;19(7):e0305034. doi: 10.1371/journal.pone.0305034. eCollection 2024. PLoS One. 2024. PMID: 38954719 Free PMC article.
Healthy humans can be a source of antibodies countering COVID-19.
Velappan N, Nguyen HB, Micheva-Viteva S, Bedinger D, Ye C, Mangadu B, Watts AJ, Meagher R, Bradfute S, Hu B, Waldo GS, Lillo AM. Velappan N, et al. Among authors: bedinger d. Bioengineered. 2022 May;13(5):12598-12624. doi: 10.1080/21655979.2022.2076390. Bioengineered. 2022. PMID: 35599623 Free PMC article.
Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study.
Hastie KM, Li H, Bedinger D, Schendel SL, Dennison SM, Li K, Rayaprolu V, Yu X, Mann C, Zandonatti M, Diaz Avalos R, Zyla D, Buck T, Hui S, Shaffer K, Hariharan C, Yin J, Olmedillas E, Enriquez A, Parekh D, Abraha M, Feeney E, Horn GQ; CoVIC-DB team1; Aldon Y, Ali H, Aracic S, Cobb RR, Federman RS, Fernandez JM, Glanville J, Green R, Grigoryan G, Lujan Hernandez AG, Ho DD, Huang KA, Ingraham J, Jiang W, Kellam P, Kim C, Kim M, Kim HM, Kong C, Krebs SJ, Lan F, Lang G, Lee S, Leung CL, Liu J, Lu Y, MacCamy A, McGuire AT, Palser AL, Rabbitts TH, Rikhtegaran Tehrani Z, Sajadi MM, Sanders RW, Sato AK, Schweizer L, Seo J, Shen B, Snitselaar JL, Stamatatos L, Tan Y, Tomic MT, van Gils MJ, Youssef S, Yu J, Yuan TZ, Zhang Q, Peters B, Tomaras GD, Germann T, Saphire EO. Hastie KM, et al. Among authors: bedinger d. Science. 2021 Oct 22;374(6566):472-478. doi: 10.1126/science.abh2315. Epub 2021 Sep 23. Science. 2021. PMID: 34554826 Free PMC article.
Assessing the binding properties of the anti-PD-1 antibody landscape using label-free biosensors.
Brown ME, Bedinger D, Lilov A, Rathanaswami P, Vásquez M, Durand S, Wallace-Moyer I, Zhong L, Nett JH, Burnina I, Caffry I, Lynaugh H, Sinclair M, Sun T, Bukowski J, Xu Y, Abdiche YN. Brown ME, et al. Among authors: bedinger d. PLoS One. 2020 Mar 5;15(3):e0229206. doi: 10.1371/journal.pone.0229206. eCollection 2020. PLoS One. 2020. PMID: 32134960 Free PMC article.
23 results