Mali P - Search Results

1

Insulin-regulated serine and lipid metabolism drive peripheral neuropathy.

Handzlik MK, Gengatharan JM, Frizzi KE, McGregor GH, Martino C, Rahman G, Gonzalez A, Moreno AM, Green CR, Guernsey LS, Lin T, Tseng P, Ideguchi Y, Fallon RJ, Chaix A, Panda S, Mali P, Wallace M, Knight R, Gantner ML, Calcutt NA, Metallo CM. Handzlik MK, et al. Among authors: mali p. Nature. 2023 Feb;614(7946):118-124. doi: 10.1038/s41586-022-05637-6. Epub 2023 Jan 25. Nature. 2023. PMID: 36697822 Free PMC article.

2

Therapeutic genome engineering via CRISPR-Cas systems.

Moreno AM, Mali P. Moreno AM, et al. Among authors: mali p. Wiley Interdiscip Rev Syst Biol Med. 2017 Jul;9(4). doi: 10.1002/wsbm.1380. Epub 2017 Feb 15. Wiley Interdiscip Rev Syst Biol Med. 2017. PMID: 28198142 Review.

3

Combinatorial CRISPR-Cas9 Metabolic Screens Reveal Critical Redox Control Points Dependent on the KEAP1-NRF2 Regulatory Axis.

Zhao D, Badur MG, Luebeck J, Magaña JH, Birmingham A, Sasik R, Ahn CS, Ideker T, Metallo CM, Mali P. Zhao D, et al. Among authors: mali p. Mol Cell. 2018 Feb 15;69(4):699-708.e7. doi: 10.1016/j.molcel.2018.01.017. Mol Cell. 2018. PMID: 29452643 Free PMC article.

4

Oligonucleotide conjugated multi-functional adeno-associated viruses.

Katrekar D, Moreno AM, Chen G, Worlikar A, Mali P. Katrekar D, et al. Among authors: mali p. Sci Rep. 2018 Feb 26;8(1):3589. doi: 10.1038/s41598-018-21742-x. Sci Rep. 2018. PMID: 29483550 Free PMC article.

5

Immune-orthogonal orthologues of AAV capsids and of Cas9 circumvent the immune response to the administration of gene therapy.

Moreno AM, Palmer N, Alemán F, Chen G, Pla A, Jiang N, Leong Chew W, Law M, Mali P. Moreno AM, et al. Among authors: mali p. Nat Biomed Eng. 2019 Oct;3(10):806-816. doi: 10.1038/s41551-019-0431-2. Epub 2019 Jul 22. Nat Biomed Eng. 2019. PMID: 31332341 Free PMC article.

6

Author Correction: Immune-orthogonal orthologues of AAV capsids and of Cas9 circumvent the immune response to the administration of gene therapy.

Moreno AM, Palmer N, Alemán F, Chen G, Pla A, Jiang N, Chew WL, Law M, Mali P. Moreno AM, et al. Among authors: mali p. Nat Biomed Eng. 2019 Oct;3(10):842. doi: 10.1038/s41551-019-0456-6. Nat Biomed Eng. 2019. PMID: 31455920

7

Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas.

Parekh U, McDonald D, Dailamy A, Wu Y, Cordes T, Zhang K, Tipps A, Metallo C, Mali P. Parekh U, et al. Among authors: mali p. iScience. 2021 Sep 20;24(10):103149. doi: 10.1016/j.isci.2021.103149. eCollection 2021 Oct 22. iScience. 2021. PMID: 34646987 Free PMC article.

8

A multilineage screen identifies actionable synthetic lethal interactions in human cancers.

Fong SH, Kuenzi BM, Mattson NM, Lee J, Sanchez K, Bojorquez-Gomez A, Ford K, Munson BP, Licon K, Bergendahl S, Shen JP, Kreisberg JF, Mali P, Hager JH, White MA, Ideker T. Fong SH, et al. Among authors: mali p. Nat Genet. 2024 Nov 18. doi: 10.1038/s41588-024-01971-9. Online ahead of print. Nat Genet. 2024. PMID: 39558023

9

Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach.

Chari R, Mali P, Moosburner M, Church GM. Chari R, et al. Among authors: mali p. Nat Methods. 2015 Sep;12(9):823-6. doi: 10.1038/nmeth.3473. Epub 2015 Jul 13. Nat Methods. 2015. PMID: 26167643 Free PMC article.

10

A multifunctional AAV-CRISPR-Cas9 and its host response.

Chew WL, Tabebordbar M, Cheng JK, Mali P, Wu EY, Ng AH, Zhu K, Wagers AJ, Church GM. Chew WL, et al. Among authors: mali p. Nat Methods. 2016 Oct;13(10):868-74. doi: 10.1038/nmeth.3993. Epub 2016 Sep 5. Nat Methods. 2016. PMID: 27595405 Free PMC article.

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