Monfregola J - Search Results

1

Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex.

Cui Z, Napolitano G, de Araujo MEG, Esposito A, Monfregola J, Huber LA, Ballabio A, Hurley JH. Cui Z, et al. Among authors: monfregola j. Nature. 2023 Feb;614(7948):572-579. doi: 10.1038/s41586-022-05652-7. Epub 2023 Jan 25. Nature. 2023. PMID: 36697823 Free PMC article.

2

Functional characterization of the TMLH gene: promoter analysis, in situ hybridization, identification and mapping of alternative splicing variants.

Monfregola J, Napolitano G, Conte I, Cevenini A, Migliaccio C, D'Urso M, Ursini MV. Monfregola J, et al. Gene. 2007 Jun 15;395(1-2):86-97. doi: 10.1016/j.gene.2007.02.012. Epub 2007 Feb 28. Gene. 2007. PMID: 17408883

3

NESCA: a new NEMO/IKKgamma and TRAF6 interacting protein.

Napolitano G, Mirra S, Monfregola J, Lavorgna A, Leonardi A, Ursini MV. Napolitano G, et al. Among authors: monfregola j. J Cell Physiol. 2009 Aug;220(2):410-7. doi: 10.1002/jcp.21782. J Cell Physiol. 2009. PMID: 19365808

4

Functional characterization of Wiskott-Aldrich syndrome protein and scar homolog (WASH), a bi-modular nucleation-promoting factor able to interact with biogenesis of lysosome-related organelle subunit 2 (BLOS2) and gamma-tubulin.

Monfregola J, Napolitano G, D'Urso M, Lappalainen P, Ursini MV. Monfregola J, et al. J Biol Chem. 2010 May 28;285(22):16951-7. doi: 10.1074/jbc.M109.078501. Epub 2010 Mar 22. J Biol Chem. 2010. PMID: 20308062 Free PMC article.

5

Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein.

Johnson JL, Monfregola J, Napolitano G, Kiosses WB, Catz SD. Johnson JL, et al. Among authors: monfregola j. Mol Biol Cell. 2012 May;23(10):1902-16. doi: 10.1091/mbc.E11-12-1001. Epub 2012 Mar 21. Mol Biol Cell. 2012. PMID: 22438581 Free PMC article.

6

MUNC13-4 protein regulates the oxidative response and is essential for phagosomal maturation and bacterial killing in neutrophils.

Monfregola J, Johnson JL, Meijler MM, Napolitano G, Catz SD. Monfregola J, et al. J Biol Chem. 2012 Dec 28;287(53):44603-18. doi: 10.1074/jbc.M112.414029. Epub 2012 Oct 31. J Biol Chem. 2012. PMID: 23115246 Free PMC article.

7

Upregulation of the Rab27a-dependent trafficking and secretory mechanisms improves lysosomal transport, alleviates endoplasmic reticulum stress, and reduces lysosome overload in cystinosis.

Johnson JL, Napolitano G, Monfregola J, Rocca CJ, Cherqui S, Catz SD. Johnson JL, et al. Among authors: monfregola j. Mol Cell Biol. 2013 Aug;33(15):2950-62. doi: 10.1128/MCB.00417-13. Epub 2013 May 28. Mol Cell Biol. 2013. PMID: 23716592 Free PMC article.

8

Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis.

Napolitano G, Johnson JL, He J, Rocca CJ, Monfregola J, Pestonjamasp K, Cherqui S, Catz SD. Napolitano G, et al. Among authors: monfregola j. EMBO Mol Med. 2015 Feb;7(2):158-74. doi: 10.15252/emmm.201404223. EMBO Mol Med. 2015. PMID: 25586965 Free PMC article.

9

Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses.

He J, Johnson JL, Monfregola J, Ramadass M, Pestonjamasp K, Napolitano G, Zhang J, Catz SD. He J, et al. Among authors: monfregola j. Mol Biol Cell. 2016 Feb 1;27(3):572-87. doi: 10.1091/mbc.E15-05-0283. Epub 2015 Dec 17. Mol Biol Cell. 2016. PMID: 26680738 Free PMC article.

10

Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth.

Di Malta C, Siciliano D, Calcagni A, Monfregola J, Punzi S, Pastore N, Eastes AN, Davis O, De Cegli R, Zampelli A, Di Giovannantonio LG, Nusco E, Platt N, Guida A, Ogmundsdottir MH, Lanfrancone L, Perera RM, Zoncu R, Pelicci PG, Settembre C, Ballabio A. Di Malta C, et al. Among authors: monfregola j. Science. 2017 Jun 16;356(6343):1188-1192. doi: 10.1126/science.aag2553. Science. 2017. PMID: 28619945 Free PMC article.

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