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Page 1
Unsupervised Classification of the Host Response Identifies Dominant Pathobiological Signatures of Sepsis in Sub-Saharan Africa.
Cummings MJ, Lutwama JJ, Owor N, Tomoiaga AS, Ross JE, Muwanga M, Nsereko C, Nayiga I, Kyebambe S, Shinyale J, Ochar T, Kiwubeyi M, Nankwanga R, Nie K, Xie H, Miake-Lye S, Villagomez B, Qi J, Reynolds SJ, Nakibuuka MC, Lu X, Kayiwa J, Haumba M, Nakaseegu J, Che X, Wayengera M, Ghosh S, Kim-Schulze S, Lipkin WI, Bakamutumaho B, O'Donnell MR. Cummings MJ, et al. Among authors: kyebambe s. Am J Respir Crit Care Med. 2024 Nov 8. doi: 10.1164/rccm.202407-1394OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 39514831
COVID-19 immune signatures in Uganda persist in HIV co-infection and diverge by pandemic phase.
Cummings MJ, Bakamutumaho B, Lutwama JJ, Owor N, Che X, Astorkia M, Postler TS, Kayiwa J, Kiconco J, Muwanga M, Nsereko C, Rwamutwe E, Nayiga I, Kyebambe S, Haumba M, Bosa HK, Ocom F, Watyaba B, Kikaire B, Tomoiaga AS, Kisaka S, Kiwanuka N, Lipkin WI, O'Donnell MR; Collaboration for Clinical and Laboratory Characterization of COVID-19 in Uganda. Cummings MJ, et al. Among authors: kyebambe s. Nat Commun. 2024 Feb 17;15(1):1475. doi: 10.1038/s41467-024-45204-3. Nat Commun. 2024. PMID: 38368384 Free PMC article.
A Transcriptomic Classifier Model Identifies High-Risk Endotypes in a Prospective Study of Sepsis in Uganda.
Cummings MJ, Bakamutumaho B, Tomoiaga AS, Owor N, Jain K, Price A, Kayiwa J, Namulondo J, Byaruhanga T, Muwanga M, Nsereko C, Nayiga I, Kyebambe S, Sameroff S, Che X, Lutwama JJ, Lipkin WI, O'Donnell MR. Cummings MJ, et al. Among authors: kyebambe s. Crit Care Med. 2024 Mar 1;52(3):475-482. doi: 10.1097/CCM.0000000000006023. Epub 2023 Aug 7. Crit Care Med. 2024. PMID: 37548511
Brief Report: Detection of Urine Lipoarabinomannan Is Associated With Proinflammatory Innate Immune Activation, Impaired Host Defense, and Organ Dysfunction in Adults With Severe HIV-Associated Tuberculosis in Uganda.
Cummings MJ, Bakamutumaho B, Jain K, Price A, Owor N, Kayiwa J, Namulondo J, Byaruhanga T, Muwanga M, Nsereko C, Nayiga I, Kyebambe S, Che X, Sameroff S, Tokarz R, Wong W, Postler TS, Larsen MH, Lipkin WI, Lutwama JJ, O'Donnell MR. Cummings MJ, et al. Among authors: kyebambe s. J Acquir Immune Defic Syndr. 2023 May 1;93(1):79-85. doi: 10.1097/QAI.0000000000003159. J Acquir Immune Defic Syndr. 2023. PMID: 36701194 Free PMC article.
HIV infection drives pro-inflammatory immunothrombotic pathway activation and organ dysfunction among adults with sepsis in Uganda.
Cummings MJ, Bakamutumaho B, Price A, Owor N, Kayiwa J, Namulondo J, Byaruhanga T, Jain K, Postler TS, Muwanga M, Nsereko C, Nayiga I, Kyebambe S, Che X, Sameroff S, Tokarz R, Shah SS, Larsen MH, Lipkin WI, Lutwama JJ, O'Donnell MR. Cummings MJ, et al. Among authors: kyebambe s. AIDS. 2023 Feb 1;37(2):233-245. doi: 10.1097/QAD.0000000000003410. Epub 2022 Oct 21. AIDS. 2023. PMID: 36355913 Free PMC article.
Epidemiology, Clinical Characteristics, and Mortality of Hospitalized Patients with Severe COVID-19 in Uganda, 2020-2021.
Bakamutumaho B, Lutwama JJ, Owor N, Kayiwa J, Kiconco J, Haumba M, Muwanga M, Nsereko C, Rwamutwe E, Nayiga I, Kyebambe S, Kyobe Bosa H, Ocom F, Watyaba B, Kikaire B, Kisaka S, Kiwanuka N, O'Donnell MR, Cummings MJ; Members of the Collaboration for Clinical and Laboratory Characterization of COVID-19 in Uganda. Bakamutumaho B, et al. Among authors: kyebambe s. Ann Am Thorac Soc. 2022 Dec;19(12):2100-2103. doi: 10.1513/AnnalsATS.202203-244RL. Ann Am Thorac Soc. 2022. PMID: 35727227 Free PMC article. No abstract available.